KIAA1407 Activators
Chemical compounds classified as KIAA1407 activators are believed to enhance the functional activity of the protein KIAA1407 through specific biochemical signaling pathways or cellular processes. Forskolin, for example, increases cAMP levels, which could enhance KIAA1407 activity if it is regulated by PKA-mediated phosphorylation. Similarly, PMA, as an activator of PKC, could augment KIAA1407 function by promoting PKC signaling, provided that KIAA1407 is involved in the PKC pathway. Growth factors like EGF, which activate the MAPK/ERK pathway, could also elevate KIAA1407's activity if KIAA1407 is regulated by or functions downstream of this pathway. These
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin directly stimulates adenylyl cyclase, increasing cyclic AMP (cAMP) levels in cells. Elevated cAMP activates protein kinase A (PKA), which can phosphorylate various proteins. If KIAA1407 is a substrate for PKA or is regulated by PKA-phosphorylated proteins, forskolin would enhance its functional activity. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA is a potent activator of protein kinase C (PKC). PKC phosphorylation can result in altered protein-protein interactions or activity. If KIAA1407 interacts with PKC substrates or is regulated by PKC-mediated signaling, its activity would be enhanced by PMA. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
Insulin activates the PI3K/Akt signaling pathway, which regulates various cellular processes, including metabolism and cell survival. If KIAA1407 is part of the PI3K/Akt pathway or is affected by it, insulin would enhance its function. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Ionomycin is a calcium ionophore that increases intracellular calcium levels, potentially activating calcium-dependent proteins. If KIAA1407 is regulated by calcium signaling, ionomycin would enhance its activity. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Isoproterenol is a non-selective beta-adrenergic agonist that increases cAMP levels, similar to forskolin. If KIAA1407 is regulated by cAMP-dependent pathways, isoproterenol would enhance its activity. | ||||||
Sodium Orthovanadate | 13721-39-6 | sc-3540 sc-3540B sc-3540A | 5 g 10 g 50 g | $49.00 $57.00 $187.00 | 142 | |
Sodium orthovanadate is an inhibitor of protein tyrosine phosphatases. By preventing dephosphorylation, it can enhance the phosphorylation state of proteins. If KIAA1407 function is enhanced by phosphorylation, orthovanadate would indirectly increase its activity. | ||||||
Spermine | 71-44-3 | sc-212953A sc-212953 sc-212953B sc-212953C | 1 g 5 g 25 g 100 g | $61.00 $196.00 $277.00 $901.00 | 1 | |
Spermine can modulate ion channels and is known to influence intracellular signaling pathways. If KIAA1407 is sensitive to changes in ionic environments or is regulated by ion channel activity, spermine would enhance its function. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $291.00 $530.00 $1800.00 | 78 | |
Okadaic acid is a potent inhibitor of serine/threonine phosphatases, such as PP1 and PP2A. Inhibition of these phosphatases can lead to increased phosphorylation levels of proteins. If KIAA1407's activity is regulated by serine/threonine phosphatase activity, okadaic acid would enhance its function. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium chloride is known to inhibit the enzyme glycogen synthase kinase-3 (GSK-3). Inhibition of GSK-3 can lead to activation of Wnt signaling and other pathways. If KIAA1407 is positively regulated by pathways antagonized by GSK-3, lithium would enhance its activity. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $99.00 $259.00 | 36 | |
Anisomycin is a protein synthesis inhibitor that can also activate stress-activated protein kinases (SAPKs) such as JNK. If KIAA1407 is regulated by or interacts with proteins in the JNK pathway, anisomycin would indirectly enhance its activity. | ||||||