KIAA0556 inhibitors represent a class of chemical compounds designed to inhibit the activity of the KIAA0556 protein, a largely uncharacterized protein implicated in cellular functions such as cytoskeletal organization and intracellular trafficking. The KIAA0556 protein belongs to a family of proteins involved in the regulation of key signaling pathways, including those related to cellular morphology, movement, and division. Inhibition of this protein has potential to reveal deeper insights into the molecular pathways it governs, especially in processes related to cellular architecture and dynamic responses to environmental stimuli. By targeting the KIAA0556 protein, researchers can modulate its activity to study its influence on actin dynamics and microtubule organization, which are fundamental to cell shape and motility.
KIAA0556 inhibitors often exhibit specificity for this protein by binding to its active or regulatory sites, preventing normal protein interactions or downstream signaling events. Structural biology approaches, including crystallography and molecular docking, aid in the design of these inhibitors, ensuring that they interact effectively with the target protein without affecting related proteins in the same pathway. Inhibition of KIAA0556 may cause observable phenotypic changes, such as altered cell migration or adhesion, which can be measured in various biological assays. These inhibitors are valuable research tools in cellular biology, offering a means to dissect the role of KIAA0556 in various physiological and experimental conditions. By studying the effects of inhibition, researchers can build a more detailed map of how this protein integrates into broader cellular processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
PI3K inhibitor that can affect signaling pathways involving protein trafficking, potentially impacting proteins like KIAA0556. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
Proteasome inhibitor that can influence protein degradation pathways, possibly affecting the stability of proteins such as KIAA0556. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
MEK inhibitor that can disrupt MAPK/ERK signaling, potentially influencing proteins associated with these pathways, including KIAA0556. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Another PI3K inhibitor that can disrupt signaling pathways, potentially affecting the function or localization of proteins like KIAA0556. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
mTOR inhibitor that can affect cell growth and autophagy pathways, potentially influencing proteins like KIAA0556 involved in these processes. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
Calcineurin inhibitor that can affect T-cell activation and other signaling pathways, potentially impacting KIAA0556 if it is involved in these pathways. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
p38 MAPK inhibitor that can disrupt inflammatory response signaling, potentially affecting proteins like KIAA0556 if they are part of this pathway. | ||||||
Bafilomycin A1 | 88899-55-2 | sc-201550 sc-201550A sc-201550B sc-201550C | 100 µg 1 mg 5 mg 10 mg | $96.00 $250.00 $750.00 $1428.00 | 280 | |
V-ATPase inhibitor that can affect vesicular trafficking and autophagy, potentially impacting proteins like KIAA0556 involved in these processes. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor that can disrupt stress response signaling, potentially affecting proteins like KIAA0556 if they are part of this pathway. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $150.00 $349.00 | 15 | |
Aurora kinase inhibitor that can affect cell division, potentially influencing proteins like KIAA0556 if they are associated with mitotic processes. | ||||||