Date published: 2026-4-1

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K12 Inhibitors

K12 inhibitors are compounds that can affect the SECTM1 protein or its associated pathways. The ERK pathway is a focal point with compounds like U0126 and PD98059 targeting MEK, which in turn affects ERK signaling. By influencing this pathway, these inhibitors might play a role in modulating SECTM1-associated processes. The JNK pathway, connected with SECTM1, can be influenced by SP600125, which directly inhibits JNK.

The PI3K-Akt pathway is vital in many cellular processes, and its association with SECTM1 makes LY294002 and Wortmannin noteworthy, as both are PI3K inhibitors. The role of mTOR in cell growth and proliferation brings Rapamycin into focus. By inhibiting mTOR, Rapamycin can modulate processes possibly linked with SECTM1. Wnt signaling is another pathway of significance. Both IWP-2, by inhibiting Wnt production, and XAV-939, by stabilizing axin, might affect SECTM1-related processes by modulating the Wnt pathway. BAY 11-7082, an NF-κB pathway inhibitor, offers another angle of intervention. Given the wide-reaching impact of NF-κB in cellular functions, its inhibition can influence SECTM1 functions.

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Items 1 to 10 of 11 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

JNK inhibitor, can affect signaling pathways potentially related to SECTM1.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

Inhibits PI3K, a key component of many signaling pathways, which might be related to SECTM1 function.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$67.00
$223.00
$425.00
97
(3)

Another PI3K inhibitor, can influence pathways that might be related to SECTM1.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$40.00
$92.00
212
(2)

Targets MEK, thereby affecting the ERK pathway that can influence SECTM1-related processes.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

Inhibits p38 MAPK, another signaling molecule that might be related to SECTM1 function.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

mTOR inhibitor, affects cell growth and proliferation processes that can be related to SECTM1.

IWP-2

686770-61-6sc-252928
sc-252928A
5 mg
25 mg
$96.00
$292.00
27
(1)

Inhibits Wnt production, affecting the Wnt signaling pathway, potentially influencing SECTM1-related pathways.

XAV939

284028-89-3sc-296704
sc-296704A
sc-296704B
1 mg
5 mg
50 mg
$36.00
$117.00
$525.00
26
(1)

Targets the Wnt pathway by stabilizing axin, which might affect SECTM1-related processes.

BAY 11-7082

19542-67-7sc-200615B
sc-200615
sc-200615A
5 mg
10 mg
50 mg
$62.00
$85.00
$356.00
155
(1)

NF-κB pathway inhibitor, a pathway that might interact with SECTM1 functions.

Stat3 inhibitor V, stattic

19983-44-9sc-202818
sc-202818A
sc-202818B
sc-202818C
sc-202818D
sc-202818E
sc-202818F
25 mg
100 mg
250 mg
500 mg
1 g
2.5 g
5 g
$130.00
$196.00
$274.00
$512.00
$731.00
$1408.00
$2091.00
114
(3)

Inhibits Stat3, which plays a role in numerous signaling pathways, potentially interacting with SECTM1.