IL-TIFb Inhibitors
IL-TIFb inhibitors belong to a class of chemical compounds specifically designed to target and interfere with the activity of a particular cytokine, often referred to as IL-TIFb. Cytokines are small proteins that play pivotal roles in mediating immune responses and various cellular processes. These inhibitors are developed to modulate the function of IL-TIFb, which may be involved in a range of immune-related functions, including inflammation, immune cell activation, and intercellular signaling.
The primary mechanism of action for IL-TIFb inhibitors typically involves their interaction with the IL-TIFb protein or its associated molecules, leading to the disruption of its normal signaling functions. By inhibiting IL-TIFb, these compounds have the potential to influence immune responses and other processes mediated by this cytokine. Researchers studying IL-TIFb inhibitors aim to elucidate the specific roles of IL-TIFb in immune regulation and cellular interactions, contributing to our understanding of its functions within the broader context of immunology. These inhibitors serve as invaluable tools for advancing our knowledge of cytokine biology and immune system function. In this context, they play a significant role in furthering our understanding of the complex network of signaling molecules that govern immune responses and cellular processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Apigenin | 520-36-5 | sc-3529 sc-3529A sc-3529B sc-3529C sc-3529D sc-3529E sc-3529F | 5 mg 100 mg 1 g 5 g 25 g 100 g 1 kg | $33.00 $214.00 $734.00 $1151.00 $2348.00 $3127.00 $5208.00 | 22 | |
Apigenin, a flavonoid, may inhibit IL-22 expression by modulating the STAT3 pathway commonly involved in the signaling of cytokines. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin is known to modulate several signaling pathways, potentially inhibiting IL-22 expression by affecting NF-κB activity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol may downregulate IL-22 expression through its action on sirtuins and modulation of the JAK-STAT pathway. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin, another flavonoid, potentially inhibits IL-22 by interfering with the PI3K-Akt pathway and subsequent STAT activation. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane might inhibit IL-22 expression by affecting NF-κB and Nrf2, which are transcription factors involved in cytokine regulation. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, the active component of green tea, may inhibit IL-22 by modulating signaling pathways like MAPK and NF-κB. | ||||||
Indirubin | 479-41-4 | sc-201531 sc-201531A | 5 mg 25 mg | $114.00 $525.00 | 4 | |
Indirubin could inhibit IL-22 expression by disrupting the activity of various kinases involved in cytokine signaling pathways. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein, an isoflavone, has potential to inhibit IL-22 expression through its action as a tyrosine kinase inhibitor. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $96.00 $160.00 $240.00 $405.00 | 26 | |
Capsaicin may downregulate IL-22 expression by affecting sensory neurons and potentially modulating neuro-immune interactions. | ||||||
Kaempferol | 520-18-3 | sc-202679 sc-202679A sc-202679B | 25 mg 100 mg 1 g | $99.00 $216.00 $510.00 | 11 | |
Kaempferol might reduce IL-22 expression by inhibiting the JAK-STAT signaling pathway and modulating transcription factor activity. | ||||||