IL-4 Activators
IL-4 activators belong to a class of chemical compounds designed to selectively target and modulate the activity of Interleukin-4 (IL-4), a cytokine that plays a critical role in the immune system. IL-4 is a multifunctional signaling protein produced by various immune cells, including T cells and mast cells, and it is involved in regulating a wide range of immune responses. IL-4 is a key player in the differentiation of T helper 2 (Th2) cells, promoting their development and orchestrating immune responses associated with allergies and parasitic infections. It also contributes to the activation of B cells and the production of immunoglobulin E (IgE), which is essential for the immune defense against parasites and certain allergens. Additionally, IL-4 has been implicated in tissue repair and remodeling processes.
Activation of IL-4 by specific chemical compounds enhance its signaling and downstream effects on immune cells. These activators are designed to promote the binding of IL-4 to its receptors on target cells, initiating intracellular signaling pathways that regulate gene expression and immune responses. The modulation of IL-4 activity can have profound effects on the immune system, influencing the balance of immune cell populations, cytokine production, and antibody responses. Understanding the mechanisms and effects of IL-4 activators is of significant interest in immunology and cellular biology research, as it can provide insights into the complex regulatory networks that govern immune responses. These compounds serve as valuable tools for investigating the roles of IL-4 in various immunological contexts and uncovering its contributions to normal immune function.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA might induce IL-4 expression by activating protein kinase C (PKC), which plays a role in T-cell activation and cytokine production, including the induction of IL-4. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
A23187 can potentially enhance IL-4 expression by increasing intracellular calcium levels, a signal that is involved in T-cell activation and cytokine production. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol could potentially induce IL-4 expression through its immunomodulatory effects, which might include modulation of T-cell activity and cytokine production. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin might affect IL-4 expression by modulating signaling pathways involved in immune response and inflammation, potentially influencing T-cell responses and cytokine production. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Cholecalciferol may influence IL-4 expression by modulating immune cell function and cytokine production, as it plays a role in immune regulation and T-cell activation. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
All-trans Retinoic Acid could potentially enhance IL-4 expression by affecting T-cell differentiation and function, as it is known to modulate immune responses. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin may modulate IL-4 expression through its anti-inflammatory and immunomodulatory effects, potentially affecting T-cell responses and cytokine production. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
DL-Sulforaphane might influence IL-4 expression by modulating antioxidant and anti-inflammatory pathways, which can affect immune cell function and cytokine production. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
(-)-Epigallocatechin Gallate could affect IL-4 expression by modulating T-cell activity and cytokine production through its anti-inflammatory and immunomodulatory properties. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Dexamethasone might modulate IL-4 expression through its anti-inflammatory actions, which include modulation of immune cell activity and cytokine production. | ||||||