IFN-α10 Inhibitors
IFN-α10 inhibitors represent a specialized class of chemical compounds designed to selectively target and modulate the function of Interferon-alpha 10 (IFN-α10). Interferons are a family of signaling proteins crucial for orchestrating immune responses against viral infections and other pathogens. IFN-α10 is a specific subtype within the interferon-alpha family, and its inhibitors are intricately designed to interact with the unique molecular structure of this signaling protein. As part of the broader interferon system, IFN-α10 plays a role in regulating antiviral defenses and immune responses, mediating the communication between cells during an immune challenge. The inhibitors developed for IFN-α10 are carefully crafted to engage with specific binding sites on the protein, aiming to disrupt its normal interactions within the cellular milieu and potentially modulate the immune signaling pathways.
The molecular architecture of IFN-α10 inhibitors is precisely tailored to interact with the unique regions of the protein, inducing changes in its conformation and dynamics. This interaction holds the potential to impact the protein's ability to transmit signals related to antiviral defenses. In laboratory research, these inhibitors serve as valuable tools, allowing scientists to explore the nuanced functions of IFN-α10 in immune responses and contributing to a deeper understanding of the intricate interplay within the immune system. By manipulating the function of IFN-α10, researchers aim to unravel the complex mechanisms of immune signaling, shedding light on the broader implications for cellular function and the orchestration of immune defenses against pathogens. The study of IFN-α10 inhibitors stands at the forefront of advancing our comprehension of immune system dynamics and the finely tuned regulation of antiviral responses.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Glucocorticoids can suppress cytokine production, including interferons, by interfering with transcription factors like NF-κB. | ||||||
Aspirin | 50-78-2 | sc-202471 sc-202471A | 5 g 50 g | $20.00 $42.00 | 4 | |
Acetylsalicylic acid (Aspirin) can inhibit the NF-κB pathway, potentially reducing IFN-α expression. | ||||||
Apigenin | 520-36-5 | sc-3529 sc-3529A sc-3529B sc-3529C sc-3529D sc-3529E sc-3529F | 5 mg 100 mg 1 g 5 g 25 g 100 g 1 kg | $33.00 $214.00 $734.00 $1151.00 $2348.00 $3127.00 $5208.00 | 22 | |
A flavone that can inhibit NF-κB activation, which may downregulate IFN-α expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin has been shown to modulate immune responses and could reduce IFN-α expression by inhibiting NF-κB. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
This compound can inhibit NF-κB signaling and might suppress IFN-α production. | ||||||
Sodium Salicylate | 54-21-7 | sc-3520 sc-3520A sc-3520B sc-3520C | 1 g 25 g 500 g 1 kg | $10.00 $26.00 $82.00 $139.00 | 8 | |
It inhibits the activation of NF-κB and could downregulate cytokine expression. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $62.00 $85.00 $356.00 | 155 | |
An inhibitor of NF-κB activation which may decrease IFN-α expression. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of c-Jun N-terminal kinase (JNK), which can regulate IFN expression. | ||||||
Pyrrolidinedithiocarbamic acid ammonium salt | 5108-96-3 | sc-203224 sc-203224A | 5 g 25 g | $33.00 $64.00 | 11 | |
A metal chelator and NF-κB inhibitor that can suppress cytokine production. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Known to modulate immune responses and potentially reduce the expression of IFN-α. | ||||||