Date published: 2025-9-10

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ICF45 Activators

ICF45 activators belong to a chemical class that interacts with a specific cellular target, the ICF45 protein. This protein is known to play a role in various cellular processes, including gene expression regulation, RNA processing, and protein synthesis. The activators are designed to bind to ICF45, leading to a conformational change or alteration in its activity, which in turn influences downstream cellular pathways. The exact mechanism of action of ICF45 activators may vary depending on the specific compound and its binding characteristics with the protein.

These activators are of interest in research settings due to their potential to modulate cellular processes mediated by ICF45. By targeting this protein, researchers aim to gain insights into fundamental biological mechanisms and potentially identify new pathways for intervention. Understanding the effects of ICF45 activators can provide valuable information about the role of ICF45 in normal cellular function.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Torin 1

1222998-36-8sc-396760
10 mg
$240.00
7
(1)

mTOR inhibitor. Given mTOR's involvement in cellular metabolism and tRNA translation, it can indirectly affect THG1L-related pathways.

Caffeine

58-08-2sc-202514
sc-202514A
sc-202514B
sc-202514C
sc-202514D
5 g
100 g
250 g
1 kg
5 kg
$32.00
$66.00
$95.00
$188.00
$760.00
13
(1)

A general kinase inhibitor. By modulating kinase activity, it can influence tRNA processing and potentially THG1L activity.

A-769662

844499-71-4sc-203790
sc-203790A
sc-203790B
sc-203790C
sc-203790D
10 mg
50 mg
100 mg
500 mg
1 g
$180.00
$726.00
$1055.00
$3350.00
$5200.00
23
(2)

AMPK activator. Given the role of AMPK in energy balance and protein synthesis, it can indirectly impact THG1L-associated functions.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

Another mTOR inhibitor, its influence on mTOR signaling can intersect with pathways potentially affecting THG1L.

Metformin-d6, Hydrochloride

1185166-01-1sc-218701
sc-218701A
sc-218701B
1 mg
5 mg
10 mg
$286.00
$806.00
$1510.00
1
(1)

An AMPK activator that can influence protein synthesis and, by extension, pathways involving THG1L.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

PI3K inhibitor. PI3K signaling affects cellular growth and metabolism, which can indirectly modulate THG1L-associated pathways.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$66.00
$219.00
$417.00
97
(3)

Another PI3K inhibitor. Its influence on cellular metabolism might indirectly modulate THG1L functions.

Cyclopamine

4449-51-8sc-200929
sc-200929A
1 mg
5 mg
$92.00
$204.00
19
(1)

Hedgehog pathway inhibitor. By altering hedgehog signaling, it might influence processes intersecting with THG1L's function.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$65.00
$267.00
257
(3)

JNK inhibitor. JNK pathways regulate various cellular processes, potentially indirectly impacting THG1L.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$88.00
$342.00
284
(5)

p38 MAPK inhibitor. By modulating the p38 MAPK pathway, it can intersect with THG1L-associated functions.