HPS-3 Activators
HPS-3 is crucial in the biogenesis of lysosome-related organelles, operating within the BLOC-2 complex. Chemicals that indirectly modulate the processes or pathways related to this function can serve as activators. ATP is indispensable, providing the required energy for a range of cellular functions, including potentially the assembly and actions of the BLOC-2 complex. Co-factors, epitomized by Magnesium chloride, might be essential for facilitating enzymatic reactions within pathways that involve HPS3.
Chemicals like IP3 and Forskolin, which play roles in intracellular signaling, can indirectly influence the biogenesis of lysosome-related organelles, thus affecting HPS3. Similarly, compounds such as Phosphatidylcholine and Sphingomyelin that shape membrane dynamics could modulate the membrane association of the BLOC-2 complex, thereby influencing HPS3. The role of Monensin and U18666A, known to perturb lysosomal function and cholesterol transport respectively, emphasizes the intricate interplay of various cellular components in maintaining organelle homeostasis. The involvement of retinoic acid in cellular differentiation further underscores the adaptability of cells and their organelles, which can be influenced by compounds that regulate HPS3 and its associated complexes.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Adenosine 5′-Triphosphate, disodium salt | 987-65-5 | sc-202040 sc-202040A | 1 g 5 g | $38.00 $74.00 | 9 | |
ATP provides energy for various cellular processes, potentially promoting BLOC-2 complex formation and function. | ||||||
Magnesium chloride | 7786-30-3 | sc-255260C sc-255260B sc-255260 sc-255260A | 10 g 25 g 100 g 500 g | $27.00 $34.00 $47.00 $123.00 | 2 | |
A co-factor in numerous enzymatic reactions, potentially supporting HPS3 function within the BLOC-2 complex. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
By elevating cAMP levels, Forskolin can influence intracellular trafficking, indirectly supporting HPS3's role. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $32.00 $66.00 $95.00 $188.00 $760.00 | 13 | |
Influences multiple cellular pathways, including those related to membrane trafficking and organelle biogenesis. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $152.00 $515.00 | ||
Known to affect lysosomal function, possibly influencing the biogenesis of lysosome-related organelles. | ||||||
C2 Ceramide | 3102-57-6 | sc-201375 sc-201375A | 5 mg 25 mg | $77.00 $316.00 | 12 | |
Influences membrane structure and trafficking; can affect lysosome-related organelle formation. | ||||||
Sodium arsenite, 0.1N Standardized Solution | 7784-46-5 | sc-301816 | 500 ml | $130.00 | 4 | |
Affects cellular stress responses which may indirectly influence organelle biogenesis and HPS3's role. | ||||||
U 18666A | 3039-71-2 | sc-203306 sc-203306A | 10 mg 50 mg | $140.00 $500.00 | 2 | |
Modulates cholesterol transport and affects lysosome function, potentially influencing HPS3 activity. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Known to influence cellular differentiation, which might alter lysosome-related organelle biogenesis. | ||||||
Sphingomyelin | 85187-10-6 | sc-201381 sc-201381A | 100 mg 500 mg | $163.00 $520.00 | 3 | |
Impacts membrane composition and dynamics, which can influence the function of the BLOC-2 complex and HPS3. | ||||||