Sodium arsenite, 0.1N Standardized Solution (CAS 7784-46-5)
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Sodium arsenite, 0.1N Standardized Solution interacts with cellular components by inhibiting enzymes involved in cellular respiration and DNA repair. It disrupts cellular processes by binding to sulfhydryl groups in proteins, leading to the inhibition of key enzymes such as pyruvate dehydrogenase and DNA ligase. This disruption ultimately leads to the impairment of ATP production and DNA repair, affecting cellular metabolism and genomic stability. sodium arsenite induces oxidative stress by generating reactive oxygen species, further contributing to cellular damage. Its mechanism of action involves the interference with cellular pathways, ultimately leading to cellular dysfunction and death.
Sodium arsenite, 0.1N Standardized Solution (CAS 7784-46-5) References
- Transportable, Chemical Genetic Methodology for the Small Molecule-Mediated Inhibition of Heat Shock Factor 1. | Moore, CL., et al. 2016. ACS Chem Biol. 11: 200-10. PMID: 26502114
- Host proteostasis modulates influenza evolution. | Phillips, AM., et al. 2017. Elife. 6: PMID: 28949290
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Sodium arsenite, 0.1N Standardized Solution, 500 ml | sc-301816 | 500 ml | $130.00 |