HnRNP H Activators represent a class of chemical compounds designed to modulate the activity of the heterogeneous nuclear ribonucleoprotein H (hnRNP H) protein. HnRNP H is a multifunctional RNA-binding protein that plays a pivotal role in various cellular processes related to RNA metabolism. It is a member of the hnRNP family, which comprises a diverse group of proteins involved in pre-mRNA splicing, RNA transport, stability, and translation regulation. HnRNP H Activators are synthesized to interact specifically with hnRNP H, influencing its cellular functions, although the precise mechanisms can vary among different compounds within this class.
HnRNP H is known to participate in the regulation of alternative splicing, mRNA stability, and the formation of RNA-protein complexes. By targeting hnRNP H, these activators impact these processes, thereby affecting gene expression and RNA processing. The modulation of hnRNP H activity by these compounds may involve direct interactions with the protein, leading to changes in its RNA-binding properties, subcellular localization, or protein-protein interactions. Consequently, hnRNP H Activators have gained significance in molecular and cellular biology research, as they offer a means to dissect the intricate mechanisms governing RNA biology and gene regulation. However, it's essential to note that the specific mechanisms and outcomes of hnRNP H activation can vary depending on the context and the particular compound used within this chemical class.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA indirectly enhances hnRNP H function by activating Protein Kinase C (PKC), which can modulate splicing factors including hnRNP H. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine, a DNA methyltransferase inhibitor, can indirectly affect hnRNP H by altering the methylation status of genes involved in its regulation. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
As an HDAC inhibitor, Sodium Butyrate can influence hnRNP H levels by altering histone acetylation and gene expression. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic Acid influences gene expression and could indirectly affect hnRNP H levels through its role in cell differentiation and proliferation. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, a major component of green tea, can modulate numerous signaling pathways, potentially influencing hnRNP H activity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
This compound from turmeric can modulate various cellular processes, potentially affecting hnRNP H levels or activity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol, found in grapes, can influence a range of cellular mechanisms, possibly affecting hnRNP H. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylate cyclase, leading to increased cAMP, which can modulate various proteins including potentially hnRNP H. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
This PI3K inhibitor can indirectly influence hnRNP H activity through its effects on cell survival and metabolism pathways. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
As an mTOR inhibitor, Rapamycin can indirectly affect hnRNP H activity by influencing cellular growth and metabolism. | ||||||