Date published: 2026-3-8

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HMG-1 Antibodies

Santa Cruz Biotechnology provides a broad selection of HMG-1 monoclonal antibodies for research focused on understanding High Mobility Group Protein 1 (HMG-1) in various biological processes. The monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). HMG-1 is a non-histone chromatin-binding protein that plays a crucial role in regulating gene expression, DNA repair, and cellular response to stress. HMG-1's involvement in inflammation and cancer progression makes it a significant target for research in both normal physiology and disease states. Understanding HMG-1 function can provide insights into therapeutic targets for various conditions. Researchers can utilize specific monoclonal antibodies to investigate HMG-1's role in DNA organization and transcriptional regulation. HMG-1 monoclonal antibodies enable detailed examination of protein-protein interactions and cellular localization patterns. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific understanding of HMG-1's biological significance.

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HMG-1 Antibodies

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HMG-1/HMGB1 Antibody (D-3)

sc-518191mouse IgG2b κ78-101 (h)WB, IP, IF, ELISAh
1
(1)

HMG-1/HMGB1 Antibody (HAP46.5)

sc-56698mouse IgG1 κFL (h)WB, IP, ELISAm, r, h
59
(18)

HMG-1/HMGB1 Antibody (B-5)

sc-518194mouse IgG1 κ78-101 (h)WB, IP, IF, IHC(P), ELISAm, r, h

new

(1)

HMG-1/HMGB1 Antibody (W-18)

sc-74085mouse IgG2bFL (h)WB, IP, IF, FCMm, r, h
19
(6)

HMG-1/HMGB1 Antibody (J2E1)

sc-135809mouse IgG2bFL (h)WB, IP, IF, IHC(P), ELISAm, r, h
11
(2)

HMG-1 CRISPR Knockout, HDR and Double Nickase Plasmids

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HMG-1/HMGB1 CRISPR/Cas9 KO Plasmid (h)

sc-400735hGene KnockoutGFP
1
(0)

HMG-1/HMGB1 HDR Plasmid (h)

sc-400735-HDRhHomology Directed RepairPuromycin
1
(0)

HMG-1/HMGB1 Double Nickase Plasmid (h)

sc-400735-NIChGene KnockoutPuromycin
1
(0)

HMG-1/HMGB1 Double Nickase Plasmid (h2)

sc-400735-NIC-2hGene KnockoutPuromycin
1
(0)

HMG-1/HMGB1 CRISPR/Cas9 KO Plasmid (m2)

sc-420871-KO-2mGene KnockoutGFP
1
(0)

HMG-1/HMGB1 HDR Plasmid (m2)

sc-420871-HDR-2mHomology Directed RepairPuromycin
1
(0)

HMG-1/HMGB1 Double Nickase Plasmid (m)

sc-420871-NICmGene KnockoutPuromycin
1
(0)

HMG-1/HMGB1 Double Nickase Plasmid (m2)

sc-420871-NIC-2mGene KnockoutPuromycin
1
(0)

HMG-1 CRISPR Activation Products

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HMG-1/HMGB1 CRISPR Activation Plasmid (h)

sc-400735-ACThGene ActivationPuro, Blast, Hygro
1
(0)

HMG-1/HMGB1 CRISPR Activation Plasmid (h2)

sc-400735-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

HMG-1/HMGB1 CRISPR Activation Plasmid (m)

sc-420871-ACTmGene ActivationPuro, Blast, Hygro
1
(0)

HMG-1/HMGB1 CRISPR Activation Plasmid (m2)

sc-420871-ACT-2mGene ActivationPuro, Blast, Hygro
1
(0)

HMG-1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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HMG-1 siRNA (m)

sc-37983mGene SilencingN/A
11
(0)

HMG-1 shRNA Plasmid (m)

sc-37983-SHmGene SilencingPuromycin
11
(0)

HMG-1 shRNA (m) Lentiviral Particles

sc-37983-VmGene SilencingPuromycin
11
(0)

HMG-1/HMGB1 siRNA (h)

sc-37982hGene SilencingN/A
26
(0)

HMG-1/HMGB1 shRNA Plasmid (h)

sc-37982-SHhGene SilencingPuromycin
26
(0)

HMG-1/HMGB1 shRNA (h) Lentiviral Particles

sc-37982-VhGene SilencingPuromycin
26
(0)

HMG-1/2/3/HMGB1/HMGB2/HMGB3 siRNA (m)

sc-270031mGene SilencingN/A
1
(0)

HMG-1/2/3/HMGB1/HMGB2/HMGB3 shRNA Plasmid (m)

sc-270031-SHmGene SilencingPuromycin
1
(0)

HMG-1/2/3/HMGB1/HMGB2/HMGB3 shRNA (m) Lentiviral Particles

sc-270031-VmGene SilencingPuromycin
1
(0)