Date published: 2026-4-27

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HepaCAM Inhibitors

HepaCAM inhibitors belong to a class of chemical compounds designed to target and modulate the activity of the HepaCAM protein, also known as Hepatocellular Carcinoma-Associated Antigen 2. HepaCAM is a transmembrane protein that has been implicated in various cellular processes, although its precise functions are still being elucidated. It was initially identified as a marker for hepatocellular carcinoma, a type of liver cancer, but subsequent research has suggested broader roles in cellular adhesion, migration, and neuronal processes. Inhibitors designed to target HepaCAM are primarily employed in molecular and cellular biology research to investigate the functional properties and regulatory mechanisms associated with this protein.

The development of HepaCAM inhibitors typically involves a combination of biochemical, biophysical, and structural approaches aimed at identifying or designing molecules that can selectively interact with HepaCAM and modulate its activity within cells. By inhibiting HepaCAM, these compounds can disrupt its roles in cellular adhesion, migration, or other processes, depending on the context. Researchers use HepaCAM inhibitors to explore the intricate roles played by this protein in cellular functions, attempting to unravel its contributions to cancer biology, neuronal development, or other processes where HepaCAM may be involved. Furthermore, these inhibitors serve as valuable tools for dissecting the broader network of cellular pathways involving HepaCAM, contributing to our understanding of fundamental cell biology mechanisms and providing insights into avenues for further scientific exploration.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

5-Azacytidine, a DNA methyltransferase inhibitor, might indirectly reduce HepaCAM expression by altering methylation patterns of DNA.

Suberoylanilide Hydroxamic Acid

149647-78-9sc-220139
sc-220139A
100 mg
500 mg
$133.00
$275.00
37
(2)

Vorinostat, an HDAC inhibitor, may indirectly decrease HepaCAM expression by changing the chromatin structure and gene expression.

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$218.00
$322.00
$426.00
7
(1)

Decitabine is another DNA methyltransferase inhibitor, which could potentially lower HepaCAM expression through DNA demethylation.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol is known to modulate multiple signaling pathways, possibly affecting the transcriptional regulation of HepaCAM.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$45.00
$164.00
$200.00
$402.00
$575.00
$981.00
$2031.00
46
(1)

Genistein, a tyrosine kinase inhibitor, may downregulate HepaCAM expression by disrupting cell signaling pathways.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin can modulate various transcription factors, potentially leading to altered HepaCAM expression.

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$90.00
$204.00
13
(1)

Triptolide is known for its broad effects on transcription, which might include decreasing HepaCAM expression.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

Sirolimus inhibits mTOR signaling and could indirectly reduce HepaCAM expression through this pathway.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

As a PI3K inhibitor, LY294002 might downregulate HepaCAM expression by affecting downstream signaling.

Wiskostatin

253449-04-6sc-204399
sc-204399A
sc-204399B
sc-204399C
1 mg
5 mg
25 mg
50 mg
$49.00
$124.00
$441.00
$828.00
4
(1)

WZB117 inhibits glucose transporter 1 (GLUT1), which might indirectly influence HepaCAM expression due to altered metabolic states.