GHS-R1 Activators
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P | 96736-12-8 | sc-361166 | 1 mg | $94.00 | 1 | |
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acts as a potent agonist for the GHS-R1 receptor, characterized by its ability to induce conformational changes that enhance receptor activation. Its unique peptide sequence facilitates specific hydrogen bonding and hydrophobic interactions, promoting a robust signaling cascade. The compound's structural integrity allows for prolonged receptor engagement, influencing various intracellular pathways and modulating physiological responses with remarkable precision. | ||||||
L-692,585 | 145455-35-2 | sc-204043 | 10 mg | $245.00 | 1 | |
L-692,585 is a selective agonist for the GHS-R1 receptor, exhibiting unique binding dynamics that stabilize the receptor's active conformation. Its distinct molecular architecture enables specific electrostatic interactions and hydrophobic contacts, enhancing receptor affinity. The compound's kinetic profile reveals rapid association and slower dissociation rates, facilitating sustained signaling. This behavior underscores its potential to modulate downstream pathways with high specificity and efficacy. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylyl cyclase, increasing cAMP levels in cells. Elevated cAMP can indirectly stimulate GHS-R1 activity by enhancing overall cell responsiveness, potentially increasing GH secretion. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates protein kinase C (PKC), which can modulate GHS-R1 signaling indirectly by altering the receptor's conformation or its associated G proteins, potentially enhancing GH release. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Caffeine, as a phosphodiesterase inhibitor, increases cAMP by preventing its breakdown. This elevation in cAMP might enhance GHS-R1 signaling, indirectly promoting GH release. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $96.00 $160.00 $240.00 $405.00 | 26 | |
Capsaicin activates TRPV1 channels, which can lead to cellular responses that indirectly activate GHS-R1 activity, possibly influencing appetite regulation. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $55.00 $125.00 | 13 | |
Pioglitazone, a PPAR-γ agonist, modulates lipid metabolism and insulin sensitivity, which might indirectly activate GHS-R1 activity, particularly in metabolic regulation. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, a major component of green tea, can modulate various signaling pathways, potentially activating GHS-R1 activity indirectly, particularly in metabolic processes. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin modulates various signaling pathways, including those related to inflammation and metabolism, which might indirectly activate GHS-R1 signaling. | ||||||