Date published: 2026-5-5

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General Crosslinkers

Santa Cruz Biotechnology now offers a broad range of crosslinkers for use in various applications. Crosslinkers are versatile chemical agents that can form covalent bonds between different molecules, thus linking them together. These compounds are crucial in scientific research for stabilizing the structure of proteins, nucleic acids, and other biomolecules, allowing for more accurate studies of their functions and interactions. By creating crosslinked networks, researchers can investigate the three-dimensional structure of macromolecules, study the dynamics of complex biological systems, and enhance the durability and functionality of biomaterials. In material science, crosslinkers are used to develop polymers with improved mechanical properties, such as increased strength and resistance to solvents and heat. Additionally, they play a vital role in developing and optimizing new materials, adhesives, coatings, and composites. The ability of crosslinkers to create strong, stable bonds has also been utilized in various biochemical techniques, such as immunoprecipitation, chromatography, and mass spectrometry, where they help in isolating and identifying specific molecules from complex mixtures. Santa Cruz Biotechnology provides a wide selection of crosslinkers, each with unique properties tailored for specific research needs, ensuring researchers have the tools necessary for their studies. View detailed information on our available crosslinkers by clicking on the product name.

Items 311 to 320 of 343 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Deoxypyridinoline Chloride Trihydrochloride Salt

204074-56-6sc-214867
500 µg
$260.00
1
(0)

Deoxypyridinoline Chloride Trihydrochloride Salt serves as an effective crosslinker, characterized by its ability to form stable covalent bonds through its reactive chloride groups. This compound exhibits a unique affinity for collagen and other proteins, facilitating the formation of intricate networks that enhance structural integrity. Its distinct reaction kinetics allow for rapid crosslinking under mild conditions, promoting efficient polymerization and contributing to the stability of biomaterials.

Biotinyl Cystamine

128915-82-2sc-210924
sc-210924A
10 mg
50 mg
$320.00
$930.00
1
(0)

Biotinyl Cystamine serves as an effective crosslinker, characterized by its ability to form stable covalent bonds through thiol-disulfide exchange reactions. This compound showcases unique reactivity due to its biotin moiety, which enhances affinity for specific biomolecules, facilitating targeted crosslinking. Its dual functional groups allow for versatile interactions, promoting complex formation and influencing polymer network properties. The kinetics of its reactions can be tailored by varying conditions, making it a valuable tool in material science.

2-[Nα-Benzoylbenzoicamido-N6-(6-biotinamidocaproyl)-L-lysinylamido]ethyl Methanethiosulfonate

910036-44-1sc-223340
5 mg
$344.00
(0)

2-[Nα-Benzoylbenzoicamido-N6-(6-biotinamidocaproyl)-L-lysinylamido]ethyl Methanethiosulfonate serves as a versatile crosslinker, characterized by its ability to form stable thioether bonds through nucleophilic attack on electrophilic sites. The presence of biotin moieties enhances its affinity for specific biomolecules, facilitating targeted interactions. Its unique structure promotes selective crosslinking, enabling tailored assembly of complex molecular networks with precise spatial organization.

Cyclophosphamide-d4

173547-45-0sc-211153
1 mg
$406.00
13
(1)

Cyclophosphamide-d4 serves as a potent crosslinker, exhibiting unique reactivity through its electrophilic phosphoramide groups. These groups facilitate the formation of covalent bonds with nucleophilic sites in biomolecules, leading to the stabilization of complex structures. Its isotopic labeling allows for precise tracking in reaction pathways, enhancing the understanding of molecular interactions. The compound's distinct kinetics promote efficient crosslinking, making it a valuable tool in polymer chemistry and materials science.

O6-[4-(Aminomethyl)benzyl]guanine

674799-96-3sc-208125
5 mg
$412.00
(0)

O6-[4-(Aminomethyl)benzyl]guanine exhibits remarkable properties as a crosslinker due to its multifunctional guanine core and the presence of an aminomethyl group. This compound facilitates robust covalent bonding through its reactive sites, enabling the formation of complex networks. Its unique structure promotes specific interactions with various substrates, enhancing the stability and durability of crosslinked materials. Additionally, the compound's ability to engage in hydrogen bonding and π-π stacking contributes to its effectiveness in creating intricate molecular architectures.

N-Fmoc-N"-succinyl-4,7,10-trioxa-1,13-tridecanediamine

172089-14-4sc-228715
1 g
$121.00
(0)

N-Fmoc-N"-succinyl-4,7,10-trioxa-1,13-tridecanediamine serves as an effective crosslinker due to its multifunctional structure, which promotes robust interactions through hydrogen bonding and electrostatic forces. Its unique arrangement of ether and amine groups enhances solubility in various solvents, allowing for versatile application in polymer networks. The compound's reactivity is characterized by rapid kinetics, enabling efficient formation of stable linkages that improve material integrity and performance.

6-(N-Trifluoroacetyl)caproic acid NHS

117032-51-6sc-478829
250 mg
$296.00
(0)

6-(N-Trifluoroacetyl)caproic acid NHS acts as a potent crosslinker, leveraging its unique trifluoroacetyl moiety to enhance reactivity with amine groups. This compound facilitates the formation of stable covalent bonds through acylation, promoting effective network formation. Its hydrophobic characteristics contribute to increased compatibility with various polymer matrices, while the presence of the NHS ester allows for selective coupling, optimizing reaction efficiency and specificity in crosslinking applications.

(S)-4-Aminobenzyl Ethylenediaminetetraacetic Acid Tetra(t-butyl) Ester

143106-46-1sc-208358
10 mg
$330.00
(0)

(S)-4-Aminobenzyl Ethylenediaminetetraacetic Acid Tetra(t-butyl) Ester serves as an effective crosslinker due to its multifunctional structure, which promotes robust interactions with polymer chains. The bulky t-butyl esters enhance steric hindrance, leading to increased reaction selectivity and stability. Its ability to form chelates with metal ions further contributes to its crosslinking efficiency, facilitating the development of complex networks with tailored mechanical properties.

1,3-Dibromo-2-propanol

96-21-9sc-229817
5 g
$30.00
(0)

1,3-Dibromo-2-propanol serves as an effective crosslinker due to its ability to form covalent bonds with nucleophilic sites in polymers. The presence of bromine atoms enhances its reactivity, facilitating rapid crosslinking under mild conditions. This compound can create three-dimensional networks, improving mechanical strength and thermal stability in materials. Its unique structure allows for selective interactions, enabling tailored modifications in polymer chemistry.

3,9-Divinyl-2,4,8,10-tetraoxaspiro[5.5]undecane

78-19-3sc-232163
5 g
$37.00
(0)

3,9-Divinyl-2,4,8,10-tetraoxaspiro[5.5]undecane serves as an innovative crosslinker, exhibiting unique reactivity through its spirocyclic structure. This compound facilitates the formation of robust networks via vinyl groups that undergo radical polymerization, enhancing material strength and thermal stability. Its distinctive tetraoxaspiro configuration promotes specific molecular interactions, leading to tailored mechanical properties in polymer matrices. The compound's ability to create intricate crosslinked architectures allows for controlled release and improved durability in various applications.