Date published: 2026-5-5

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General Crosslinkers

Santa Cruz Biotechnology now offers a broad range of crosslinkers for use in various applications. Crosslinkers are versatile chemical agents that can form covalent bonds between different molecules, thus linking them together. These compounds are crucial in scientific research for stabilizing the structure of proteins, nucleic acids, and other biomolecules, allowing for more accurate studies of their functions and interactions. By creating crosslinked networks, researchers can investigate the three-dimensional structure of macromolecules, study the dynamics of complex biological systems, and enhance the durability and functionality of biomaterials. In material science, crosslinkers are used to develop polymers with improved mechanical properties, such as increased strength and resistance to solvents and heat. Additionally, they play a vital role in developing and optimizing new materials, adhesives, coatings, and composites. The ability of crosslinkers to create strong, stable bonds has also been utilized in various biochemical techniques, such as immunoprecipitation, chromatography, and mass spectrometry, where they help in isolating and identifying specific molecules from complex mixtures. Santa Cruz Biotechnology provides a wide selection of crosslinkers, each with unique properties tailored for specific research needs, ensuring researchers have the tools necessary for their studies. View detailed information on our available crosslinkers by clicking on the product name.

Items 321 to 330 of 343 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Diethyl acetylenedicarboxylate

762-21-0sc-234652
sc-234652A
5 g
25 g
$23.00
$72.00
(0)

Diethyl acetylenedicarboxylate serves as an effective crosslinker due to its ability to undergo Diels-Alder reactions, facilitating the formation of robust polymer networks. Its unique structure allows for multiple reactive sites, promoting diverse crosslinking pathways. The compound exhibits high reactivity with nucleophiles, enabling rapid formation of covalent bonds. Additionally, its electron-withdrawing groups enhance electrophilicity, influencing reaction kinetics and leading to tailored material properties.

N-Maleimidomethanol

5063-96-7sc-219170
250 mg
$245.00
(0)

N-Maleimidomethanol is a versatile crosslinker known for its ability to form stable covalent bonds with thiol groups, enabling the creation of robust polymer networks. Its unique structure allows for selective reactivity, facilitating controlled crosslinking in various conditions. The compound exhibits favorable reaction kinetics, promoting efficient coupling at ambient temperatures. Additionally, its hydrophilic nature enhances solubility in aqueous environments, making it suitable for diverse applications in material science.

2,2′-Sulfonyldiethanol solution

2580-77-0sc-225583
25 g
$65.00
(0)

2,2'-Sulfonyldiethanol solution serves as an effective crosslinker, exhibiting unique reactivity through its sulfonyl and hydroxyl functional groups. This compound promotes the formation of robust networks by facilitating covalent bonding between polymer chains, enhancing mechanical properties. Its ability to engage in hydrogen bonding and dipole-dipole interactions contributes to its stability and compatibility with various materials, making it a key player in polymer chemistry.

1,4-Butanediyl diglycidyl ether

2425-79-8sc-251594
10 g
$92.00
(0)

1,4-Butanediyl diglycidyl ether serves as an effective crosslinker, exhibiting a unique ability to form robust three-dimensional networks through its epoxide groups. These reactive sites facilitate ring-opening reactions with nucleophiles, leading to enhanced mechanical properties in polymer matrices. The compound's flexible aliphatic chain contributes to improved compatibility with various substrates, while its low viscosity promotes even distribution during processing, ensuring uniform crosslinking.

1,4-Bis(triethoxysilyl)benzene

2615-18-1sc-253986
sc-253986A
sc-253986B
sc-253986C
5 g
20 g
100 g
500 g
$140.00
$371.00
$1796.00
$6125.00
(0)

1,4-Bis(triethoxysilyl)benzene serves as an effective crosslinker, featuring multiple triethoxysilyl groups that facilitate robust silane bonding with various substrates. Its unique structure promotes extensive network formation through siloxane linkages, enhancing mechanical strength and thermal stability. The compound exhibits rapid reaction kinetics, allowing for efficient curing processes. Additionally, its hydrophobic characteristics contribute to improved water resistance in polymer matrices, making it suitable for diverse applications.

4-Arm PEG-Epoxide

sc-360238
1 g
$300.00
(0)

4-Arm PEG-Epoxide serves as a versatile crosslinker, characterized by its branched structure that enhances molecular connectivity. Its epoxide groups enable rapid and selective reactions with nucleophiles, facilitating the formation of robust networks. The polymer's hydrophilicity promotes water solubility, while its flexible arms allow for spatial adaptability in various matrices. This unique architecture supports tailored mechanical properties and reaction kinetics, making it suitable for diverse applications in material science.

1,2-Bis(2-iodoethoxy)ethane

36839-55-1sc-222786
5 g
$32.00
(0)

1,2-Bis(2-iodoethoxy)ethane serves as an effective crosslinker due to its unique bifunctional structure, enabling robust covalent bonding through its iodoethoxy groups. These groups facilitate nucleophilic attack, promoting rapid crosslinking reactions with various substrates. The compound's ability to form stable networks enhances mechanical properties and thermal stability in polymer matrices, while its reactivity can be finely tuned by adjusting reaction conditions, allowing for tailored material performance.

Tris[3-(trimethoxysilyl)propyl] isocyanurate

26115-70-8sc-253798
100 ml
$105.00
(0)

Tris[3-(trimethoxysilyl)propyl] isocyanurate serves as an effective crosslinker, exhibiting remarkable reactivity due to its isocyanurate core. This compound facilitates the formation of robust siloxane networks through hydrolysis and condensation reactions, enhancing material durability. Its trimethoxysilyl groups promote strong adhesion to various substrates, while the unique trifunctional structure allows for versatile crosslinking pathways, resulting in improved mechanical properties and thermal stability in polymer matrices.

Trimethylolpropane tris(3-mercaptopropionate)

33007-83-9sc-237349
100 ml
$37.00
(0)

Trimethylolpropane tris(3-mercaptopropionate) serves as an effective crosslinker, exhibiting remarkable thiol reactivity that promotes the formation of robust thioether linkages. Its multifunctional nature allows for rapid polymerization, enhancing network density and mechanical strength in polymer matrices. The compound's unique ability to facilitate dynamic covalent bonding contributes to its versatility in creating tailored materials with specific thermal and chemical resistance properties, optimizing performance in diverse applications.

9-Diethylamino-5-(4,6-dichloro-s-triazinyl)-9H-benzo[a]phenoxazine Chloride

28249-90-3sc-207220
5 mg
$330.00
(0)

9-Diethylamino-5-(4,6-dichloro-s-triazinyl)-9H-benzo[a]phenoxazine Chloride exhibits remarkable crosslinking capabilities due to its highly reactive triazine moiety, which facilitates nucleophilic attack and covalent bond formation. The compound's electron-rich aromatic system enhances π-π stacking interactions, promoting structural integrity in polymer matrices. Its unique chlorinated structure also influences solubility and compatibility with various substrates, making it a versatile agent in crosslinking applications.