Date published: 2026-2-3

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General Crosslinkers

Santa Cruz Biotechnology now offers a broad range of crosslinkers for use in various applications. Crosslinkers are versatile chemical agents that can form covalent bonds between different molecules, thus linking them together. These compounds are crucial in scientific research for stabilizing the structure of proteins, nucleic acids, and other biomolecules, allowing for more accurate studies of their functions and interactions. By creating crosslinked networks, researchers can investigate the three-dimensional structure of macromolecules, study the dynamics of complex biological systems, and enhance the durability and functionality of biomaterials. In material science, crosslinkers are used to develop polymers with improved mechanical properties, such as increased strength and resistance to solvents and heat. Additionally, they play a vital role in developing and optimizing new materials, adhesives, coatings, and composites. The ability of crosslinkers to create strong, stable bonds has also been utilized in various biochemical techniques, such as immunoprecipitation, chromatography, and mass spectrometry, where they help in isolating and identifying specific molecules from complex mixtures. Santa Cruz Biotechnology provides a wide selection of crosslinkers, each with unique properties tailored for specific research needs, ensuring researchers have the tools necessary for their studies. View detailed information on our available crosslinkers by clicking on the product name.

Items 331 to 340 of 344 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

9-Diethylamino-5-(4,6-dichloro-s-triazinyl)-9H-benzo[a]phenoxazine Chloride

28249-90-3sc-207220
5 mg
$330.00
(0)

9-Diethylamino-5-(4,6-dichloro-s-triazinyl)-9H-benzo[a]phenoxazine Chloride exhibits remarkable crosslinking capabilities due to its highly reactive triazine moiety, which facilitates nucleophilic attack and covalent bond formation. The compound's electron-rich aromatic system enhances π-π stacking interactions, promoting structural integrity in polymer matrices. Its unique chlorinated structure also influences solubility and compatibility with various substrates, making it a versatile agent in crosslinking applications.

4′-Aminomethyltrioxsalen hydrochloride

62442-61-9sc-214292
5 mg
$136.00
1
(1)

4'-Aminomethyltrioxsalen hydrochloride serves as an effective crosslinker, characterized by its ability to form stable covalent bonds through photochemical activation. The compound's unique trioxsalen structure allows for interstrand crosslinking via specific interactions with nucleic acids, enhancing structural cohesion. Its high reactivity under UV light promotes rapid crosslinking kinetics, while its hydrophilic nature improves compatibility with diverse polymer systems, facilitating tailored material properties.

Trimethylolpropane trimethacrylate

3290-92-4sc-237347
sc-237347A
100 g
500 g
$32.00
$60.00
(0)

Trimethylolpropane trimethacrylate serves as an effective crosslinker due to its multifunctional nature, enabling the formation of robust polymer networks. Its three methacrylate groups facilitate rapid radical polymerization, enhancing reaction kinetics and promoting efficient crosslinking. The compound's ability to create dense, three-dimensional structures contributes to improved mechanical properties and thermal stability in polymer matrices, making it a key player in material science applications.

N-Fmoc-1,4-butanediamine hydrobromide

352235-99-5sc-301345
1 g
$197.00
(0)

N-Fmoc-1,4-butanediamine hydrobromide serves as an effective crosslinker due to its bifunctional amine groups, which enable robust covalent bonding through nucleophilic attack. The presence of the Fmoc protecting group enhances its stability and solubility, facilitating controlled reactions in polymer synthesis. Its ability to form stable networks through dynamic covalent interactions allows for tailored material properties, making it suitable for diverse applications in polymer chemistry and materials science.

Digoxigenin NHS ester

129273-26-3sc-471682
sc-471682A
1 mg
5 mg
$255.00
$877.00
1
(0)

Digoxigenin NHS ester serves as a versatile crosslinker, notable for its selective reactivity with nucleophiles, particularly amines. The presence of the NHS moiety allows for rapid and efficient coupling, promoting the formation of stable covalent bonds. Its unique structural features enable precise control over reaction kinetics, while the compound's amphiphilic nature aids in modulating interactions in various biochemical contexts, enhancing the specificity of conjugation processes.

Di(ethylene glycol) dimethacrylate

2358-84-1sc-234545
250 ml
$79.00
(0)

Di(ethylene glycol) dimethacrylate serves as an effective crosslinker, facilitating the formation of robust polymer networks through its dual methacrylate groups. These groups enable rapid radical polymerization, enhancing the material's mechanical strength and thermal stability. The compound's flexible ether linkages contribute to its compatibility with various monomers, promoting uniform crosslinking. Additionally, its low viscosity allows for easy processing, making it ideal for applications requiring precise control over polymer architecture.

1,4-Butanediol diacrylate

1070-70-8sc-223020
sc-223020A
sc-223020B
sc-223020C
sc-223020D
25 ml
100 ml
1 L
20 L
60 L
$37.00
$57.00
$287.00
$1873.00
$4815.00
1
(1)

1,4-Butanediol diacrylate is a highly effective crosslinker known for its ability to form dense, three-dimensional networks through radical polymerization. Its dual acrylate functionality promotes rapid reaction kinetics, enabling efficient curing processes. The compound exhibits strong intermolecular interactions, enhancing mechanical strength and thermal stability in polymer matrices. Its low viscosity facilitates even distribution in formulations, ensuring uniform crosslinking and improved material performance.

Dichlorobis(trimethylphosphine)nickel(II)

19232-05-4sc-252699
1 g
$52.00
(0)

Dichlorobis(trimethylphosphine)nickel(II) serves as an effective crosslinker, exhibiting unique coordination chemistry through its metal-ligand interactions. The nickel center facilitates the formation of stable complexes with various substrates, enhancing polymer network formation. Its ability to engage in oxidative addition and reductive elimination pathways allows for tailored reactivity, while the steric bulk of the trimethylphosphine ligands influences the spatial arrangement of crosslinked structures, promoting diverse material properties.

N-[2-[2-[2-[(N-Biotinyl-caproylamino)-ethoxy)ethoxyl]-4-[2-(trifluoromethyl)-3H-diazirin-3-yl]benzoyl]-1,3-bis(mannopyranosyl-4-yloxy)-2-propylamine

207971-25-3sc-224114
250 µg
$440.00
(0)

N-[2-[2-[2-[(N-Biotinyl-caproylamino)-ethoxy)ethoxyl]-4-[2-(trifluoromethyl)-3H-diazirin-3-yl]benzoyl]-1,3-bis(mannopyranosyl-4-yloxy)-2-propylamine serves as a potent crosslinker, exhibiting unique molecular interactions through its multifunctional structure. The presence of mannopyranosyl units enhances its ability to form stable networks, while the trifluoromethyl group contributes to its hydrophobic character, influencing solubility and reactivity in diverse environments. Its intricate design allows for selective binding and crosslinking, facilitating complex polymer architectures.

1-Biotinylamino-3,6,9-trioxaundecane-11-yl-methanethiosulfonate

sc-213313
10 mg
$360.00
(0)

1-Biotinylamino-3,6,9-trioxaundecane-11-yl-methanethiosulfonate functions as an effective crosslinker, characterized by its unique trioxaundecane backbone that promotes robust molecular interactions. The methanethiosulfonate moiety enhances thiol reactivity, enabling efficient covalent bonding in various conditions. Its structural versatility allows for tailored crosslinking pathways, facilitating the formation of intricate polymer networks with distinct mechanical properties and stability.