Date published: 2026-5-5

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General Crosslinkers

Santa Cruz Biotechnology now offers a broad range of crosslinkers for use in various applications. Crosslinkers are versatile chemical agents that can form covalent bonds between different molecules, thus linking them together. These compounds are crucial in scientific research for stabilizing the structure of proteins, nucleic acids, and other biomolecules, allowing for more accurate studies of their functions and interactions. By creating crosslinked networks, researchers can investigate the three-dimensional structure of macromolecules, study the dynamics of complex biological systems, and enhance the durability and functionality of biomaterials. In material science, crosslinkers are used to develop polymers with improved mechanical properties, such as increased strength and resistance to solvents and heat. Additionally, they play a vital role in developing and optimizing new materials, adhesives, coatings, and composites. The ability of crosslinkers to create strong, stable bonds has also been utilized in various biochemical techniques, such as immunoprecipitation, chromatography, and mass spectrometry, where they help in isolating and identifying specific molecules from complex mixtures. Santa Cruz Biotechnology provides a wide selection of crosslinkers, each with unique properties tailored for specific research needs, ensuring researchers have the tools necessary for their studies. View detailed information on our available crosslinkers by clicking on the product name.

Items 301 to 310 of 343 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Triethylenetetramine

112-24-3sc-251328
sc-251328A
sc-251328B
sc-251328C
sc-251328D
100 g
500 g
1 kg
2 kg
18 kg
$31.00
$35.00
$73.00
$116.00
$640.00
1
(0)

Triethylenetetramine, a polyamine, serves as an effective crosslinker due to its multiple amine groups, which facilitate strong hydrogen bonding and ionic interactions with various substrates. Its branched structure enhances network formation, promoting increased mechanical strength and thermal stability in polymer matrices. The compound's reactivity is characterized by rapid amine-epoxy reactions, allowing for efficient curing processes and tailored material properties in diverse applications.

4′-(3-Trifluoromethyl-3H-diazirin-3-yl)-2′-tributylstannylbenzyl Benzoate

sc-474525
1 mg
$490.00
(0)

4'-(3-Trifluoromethyl-3H-diazirin-3-yl)-2'-tributylstannylbenzyl Benzoate serves as an innovative crosslinker, characterized by its unique trifluoromethyl group that enhances reactivity and stability. The diazirine moiety allows for photochemical activation, enabling precise control over crosslinking processes. Its tributyltin component contributes to robust covalent bonding, facilitating the formation of complex networks. This compound's distinctive properties promote tailored interactions in polymer chemistry, enhancing material performance.

1,3,5-Tris(4-aminophenoxy)benzene

102852-92-6sc-475505
500 mg
$380.00
(0)

1,3,5-Tris(4-aminophenoxy)benzene serves as an effective crosslinker due to its multifunctional amine groups, which enable robust covalent bonding with various polymer matrices. Its unique structural arrangement promotes extensive network formation, enhancing mechanical strength and thermal stability in composite materials. The compound's ability to engage in hydrogen bonding and π-π stacking interactions further contributes to its efficacy, facilitating tailored properties in advanced material applications.

Undecane-1,11-diyl-bismethanethiosulfonate

sc-475675
10 mg
$380.00
(0)

Undecane-1,11-diyl-bismethanethiosulfonate serves as an effective crosslinker due to its unique bifunctional structure, which promotes the formation of robust covalent bonds between polymer chains. Its long hydrocarbon backbone enhances flexibility, while the thiosulfonate groups facilitate nucleophilic attack, leading to rapid crosslinking kinetics. This compound's ability to create three-dimensional networks contributes to improved mechanical properties and thermal stability in polymer matrices.

N-t-Boc-2-bromoethylamine

39684-80-5sc-219234
1 g
$184.00
(0)

N-t-Boc-2-bromoethylamine serves as an effective crosslinker due to its reactive bromoethylamine moiety, which facilitates nucleophilic substitution reactions. This compound exhibits a unique ability to form stable covalent bonds with amine and thiol groups, enhancing polymer network formation. Its sterically hindered Boc protecting group allows for controlled reactivity, enabling selective crosslinking in complex systems. The compound's solubility in organic solvents further aids in its integration into various polymer matrices.

2-[2-[2-[2-[6-(Biotinylaminohexanoyl]aminoethoxy]ethoxy]ethoxy]-4-[3-(trifluoromethyl)-3H-diazirin-3-yl]benzoic Acid

207971-23-1sc-206353
1 mg
$430.00
(0)

2-[2-[2-[2-[6-(Biotinylaminohexanoyl]aminoethoxy]ethoxy]ethoxy]-4-[3-(trifluoromethyl)-3H-diazirin-3-yl]benzoic Acid serves as a potent crosslinker, characterized by its ability to form stable covalent bonds through its diazirine moiety, which undergoes photochemical activation. This compound exhibits selective reactivity towards amines and carboxylic acids, enabling precise targeting in complex biological systems. Its biotinylated structure enhances affinity for streptavidin, facilitating effective conjugation and immobilization strategies. The trifluoromethyl group contributes to its unique electronic properties, influencing reaction kinetics and enhancing solubility in organic solvents.

1,17-Bisbiotinylamino-3,6,9,12,15-pentaoxaheptadecane

440680-87-5sc-206218
25 mg
$280.00
(0)

1,17-Bisbiotinylamino-3,6,9,12,15-pentaoxaheptadecane functions as an innovative crosslinker, distinguished by its dual biotinylation, which promotes strong interactions with streptavidin. Its unique polyether backbone enhances solubility and flexibility, allowing for efficient spatial organization in complex assemblies. The compound's ability to form stable linkages through amine and carboxylic acid interactions enables tailored connectivity in diverse applications, optimizing structural integrity and functionality.

3-[(2-Aminoethyl)dithio]propionic Acid

15579-00-7sc-209496
100 mg
$398.00
(0)

3-[(2-Aminoethyl)dithio]propionic Acid functions as an effective crosslinker, exhibiting unique thiol-disulfide exchange reactions that enhance polymer network formation. Its bifunctional nature allows for the creation of robust covalent bonds, promoting structural integrity in various materials. The compound's ability to facilitate dynamic crosslinking under mild conditions leads to tailored mechanical properties, while its reactivity with various substrates enables diverse applications in material science.

N-Biotinylcaproylaminocaproic Acid

89889-51-0sc-212137
25 mg
$306.00
(0)

N-Biotinylcaproylaminocaproic Acid serves as a versatile crosslinker, characterized by its ability to form stable amide bonds through nucleophilic acyl substitution. This compound's unique biotinylation enhances molecular recognition, facilitating specific interactions within polymer matrices. Its moderate reactivity allows for controlled crosslinking kinetics, enabling the fine-tuning of material properties. Additionally, the presence of multiple functional groups promotes diverse connectivity, enhancing the structural complexity of the resulting networks.

Angelicin

523-50-2sc-210817
sc-210817A
10 mg
25 mg
$253.00
$465.00
(0)

Angelicin serves as an effective crosslinker, exhibiting unique reactivity through its ability to form covalent bonds with nucleophilic sites in polymers. Its distinct molecular structure allows for selective interactions, enhancing the mechanical properties of composite materials. The compound's reactivity is influenced by its conjugated system, which facilitates rapid crosslinking kinetics. Additionally, Angelicin's solubility in various solvents contributes to its versatility in modifying polymer networks, promoting tailored material characteristics.