Date published: 2026-5-5

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General Crosslinkers

Santa Cruz Biotechnology now offers a broad range of crosslinkers for use in various applications. Crosslinkers are versatile chemical agents that can form covalent bonds between different molecules, thus linking them together. These compounds are crucial in scientific research for stabilizing the structure of proteins, nucleic acids, and other biomolecules, allowing for more accurate studies of their functions and interactions. By creating crosslinked networks, researchers can investigate the three-dimensional structure of macromolecules, study the dynamics of complex biological systems, and enhance the durability and functionality of biomaterials. In material science, crosslinkers are used to develop polymers with improved mechanical properties, such as increased strength and resistance to solvents and heat. Additionally, they play a vital role in developing and optimizing new materials, adhesives, coatings, and composites. The ability of crosslinkers to create strong, stable bonds has also been utilized in various biochemical techniques, such as immunoprecipitation, chromatography, and mass spectrometry, where they help in isolating and identifying specific molecules from complex mixtures. Santa Cruz Biotechnology provides a wide selection of crosslinkers, each with unique properties tailored for specific research needs, ensuring researchers have the tools necessary for their studies. View detailed information on our available crosslinkers by clicking on the product name.

Items 291 to 300 of 343 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline

16357-59-8sc-254228
sc-254228A
5 g
25 g
$26.00
$49.00
(0)

2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline serves as a versatile crosslinker, distinguished by its ability to engage in multiple hydrogen bonding interactions. Its unique structure promotes selective reactivity, allowing for tailored crosslinking pathways that enhance network stability. The compound's moderate reactivity facilitates controlled polymerization processes, resulting in robust materials with improved mechanical properties. Additionally, its solubility characteristics enable effective dispersion in various matrices, optimizing performance in diverse applications.

4-Nitrophenyl chloroformate

7693-46-1sc-254713
sc-254713A
sc-254713B
5 g
25 g
100 g
$75.00
$190.00
$595.00
(0)

4-Nitrophenyl chloroformate acts as an effective crosslinker, characterized by its electrophilic nature that facilitates acylation reactions with nucleophiles. This compound exhibits rapid reaction kinetics, enabling swift formation of stable linkages in polymer networks. Its unique nitro group enhances electron-withdrawing properties, promoting selective reactivity. The resulting crosslinked structures demonstrate increased thermal stability and mechanical integrity, making them suitable for advanced material applications.

Woodward′s reagent K

4156-16-5sc-251746
1 g
$317.00
(0)

Woodward's reagent K serves as a potent crosslinker, distinguished by its ability to form robust covalent bonds through acylation with nucleophilic sites. Its unique structure allows for selective interactions with amines and alcohols, leading to the formation of stable linkages. The reagent's reactivity is influenced by steric factors, enabling tailored crosslinking in diverse polymer matrices. This results in enhanced material properties, including improved elasticity and resistance to degradation.

Benzophenone-4-carboxamidocysteine Methanethiosulfonate

317821-69-5sc-217724
10 mg
$374.00
(0)

Benzophenone-4-carboxamidocysteine Methanethiosulfonate acts as an effective crosslinker, characterized by its ability to engage in thiol-disulfide exchange reactions. This compound features a unique thiol group that facilitates the formation of disulfide bonds, enhancing network stability. Its reactivity is modulated by the presence of electron-withdrawing groups, allowing for controlled crosslinking kinetics. This results in materials with improved mechanical strength and thermal stability.

N-Hydroxysuccinimide

6066-82-6sc-219162A
sc-219162
sc-219162B
sc-219162C
sc-219162D
sc-219162E
25 g
100 g
250 g
1 kg
5 kg
10 kg
$40.00
$53.00
$94.00
$166.00
$385.00
$719.00
(0)

N-Hydroxysuccinimide serves as an effective crosslinker due to its ability to form stable amide bonds through nucleophilic attack by primary amines. Its cyclic structure facilitates rapid reaction kinetics, promoting efficient coupling in diverse environments. The compound's polar nature enhances solubility in aqueous solutions, while its reactivity is influenced by the presence of electron-withdrawing groups, allowing for selective targeting in polymerization processes.

Sulfo-SBED

sc-397353
10 mg
$576.00
(0)

Sulfo-SBED is a versatile crosslinker characterized by its unique sulfonate group, which enhances solubility in aqueous environments and promotes efficient conjugation with biomolecules. Its reactive sulfonyl chloride moiety facilitates rapid covalent bonding with nucleophiles, enabling precise control over crosslinking density. The compound's ability to form stable sulfonamide linkages contributes to its effectiveness in creating robust networks, while its distinct electronic properties allow for selective interactions in complex systems.

Furazolidone

67-45-8sc-218546
sc-218546A
10 g
100 g
$89.00
$260.00
(0)

Furazolidone functions as a crosslinker through its unique ability to form covalent bonds with nucleophilic sites in polymers. Its nitro and furan moieties contribute to its reactivity, enabling it to engage in electrophilic addition reactions. The compound's planar structure enhances π-π stacking interactions, which can stabilize crosslinked networks. Furthermore, its electron-withdrawing groups can modulate reaction rates, allowing for controlled crosslinking under specific conditions.

Dimethyl suberimidate dihydrochloride

34490-86-3sc-239782
5 g
$80.00
(0)

Dimethyl suberimidate dihydrochloride serves as an effective crosslinker due to its ability to form imide bonds through nucleophilic attack on its electrophilic sites. This compound exhibits a high degree of specificity in crosslinking reactions, promoting the formation of robust networks in polymer matrices. Its dual hydrochloride form enhances solubility in aqueous environments, facilitating easier handling and application in various chemical processes. The compound's reactivity profile allows for controlled crosslinking, enabling tailored material properties.

Methotrexyl Tobramycin Amide Formate

sc-218709
1 mg
$360.00
(0)

Methotrexyl Tobramycin Amide Formate serves as an effective crosslinker, exhibiting unique reactivity through its amide and formate functionalities. Its ability to form stable covalent bonds is influenced by specific steric and electronic interactions, which enhance its compatibility with various substrates. The compound's distinctive reaction kinetics allow for controlled polymerization processes, while its molecular structure promotes selective binding, facilitating tailored material properties in crosslinked networks.

N-(2-Aminoethyl)maleimide Trifluoroacetic Acid

146474-00-2sc-358381
500 mg
$280.00
3
(1)

N-(2-Aminoethyl)maleimide Trifluoroacetic Acid serves as an effective crosslinker due to its reactive maleimide group, which readily forms stable thioether bonds with sulfhydryl-containing molecules. This compound exhibits unique reactivity profiles, allowing for selective conjugation under mild conditions. Its trifluoroacetic acid component enhances solubility and stability in various solvents, facilitating efficient reaction kinetics. The presence of the aminoethyl moiety further promotes molecular interactions, enabling tailored crosslinking strategies in diverse applications.