Molecular structure of 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline, CAS Number: 16357-59-8
2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline (CAS 16357-59-8)
Alternate Names:
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; EEDQ
Application:
2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline is an irreversible membrane-bound receptor antagonist
CAS Number:
16357-59-8
Molecular Weight:
247.29
Molecular Formula:
C14H17NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline is a compound that functions as a potential inhibitor. It is known to interact with specific molecular targets, disrupting their activity and potentially altering cellular processes. 2-Ethoxy-1-Ethoxycarbonyl-1,2-Dihydroquinoline has been studied for its ability to modulate certain biological pathways, which may provide insights into the underlying mechanisms of various cellular functions. Its mechanism of action involves binding to specific sites within the target molecules, thereby interfering with their normal function. This interaction at the molecular level has been of interest in elucidating the role of these targets in cellular processes. 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline has exhibted promise as a function for investigating the molecular mechanisms underlying certain biological phenomena.
2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline (CAS 16357-59-8) References
- N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline studies on the role of 5-HT1A and 5-HT2 receptors in mediating foot-shock-induced ultrasonic vocalisation in adult rats. | Sánchez, C. and Mørk, A. 1999. Eur Neuropsychopharmacol. 9: 287-94. PMID: 10422888
- Effects of alpha 2-adrenoceptor agonists on locus coeruleus firing rate and brain noradrenaline turnover in N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ)-treated rats. | Engberg, G. and Eriksson, E. 1991. Naunyn Schmiedebergs Arch Pharmacol. 343: 472-7. PMID: 1652697
- Relative efficacy of spinal alpha-2 agonists, dexmedetomidine, clonidine and ST-91, determined in vivo by using N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, an irreversible antagonist. | Takano, Y. and Yaksh, TL. 1991. J Pharmacol Exp Ther. 258: 438-46. PMID: 1678011
- Influence of N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline modification on proton translocation and membrane potential of reconstituted cytochrome-c oxidase support 'proton slippage'. | Steverding, D. and Kadenbach, B. 1991. J Biol Chem. 266: 8097-101. PMID: 1850736
- Inactivation of D1 and D2 dopamine receptors by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline in vivo: selective protection by neuroleptics. | Meller, E., et al. 1985. J Pharmacol Exp Ther. 233: 656-62. PMID: 2861276
- The use of [3H]aniline to identify the essential carboxyl group in the bovine mitochondrial F1-ATPase that reacts with 1-(ethoxycarbonyl)-2-ethoxy-1,2-dihydroquinoline. | Laikind, PK., et al. 1985. Arch Biochem Biophys. 240: 904-20. PMID: 2862844
- Recovery of alpha 2-adrenoceptor binding and function after irreversible inactivation by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ). | Adler, CH., et al. 1985. Eur J Pharmacol. 116: 175-8. PMID: 2865161
- N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ): a new tool to probe CNS receptor function. | Meller, E., et al. 1988. Adv Exp Med Biol. 235: 121-36. PMID: 2906517
- N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, amiloride analogues, and renal Na+/H+ antiporter. | Rocco, VK., et al. 1987. Am J Physiol. 252: F517-24. PMID: 3030138
- Behavioral and radioligand binding evidence for irreversible dopamine receptor blockade by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline. | Hamblin, MW. and Creese, I. 1983. Life Sci. 32: 2247-55. PMID: 6133202
- An autoradiographic study of the differential effects of N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) on striatal and extrastriatal D-1 and D-2 dopamine receptors in the rat. | Gnanalingham, KK., et al. 1994. Neuropharmacology. 33: 647-55. PMID: 7936100
- Differential effects of N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) on various 5-HT receptor binding sites in the rat brain. | Gozlan, H., et al. 1994. Neuropharmacology. 33: 423-31. PMID: 7984280
- Differential effects of the alkylating agent N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline on brain alpha 2-adrenoceptors and I2-imidazoline sites in vitro and in vivo. | Miralles, A., et al. 1993. J Neurochem. 61: 1602-10. PMID: 8228980
- Irreversible antagonism of 5HT2c receptors by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ). | Ni, YG., et al. 1997. Proc Natl Acad Sci U S A. 94: 2715-8. PMID: 9122262
- N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) administration for studies of 5-HT1A receptor binding site inactivation and turnover. | Keck, BJ. and Lakoski, JM. 1997. Brain Res Brain Res Protoc. 1: 364-70. PMID: 9384817
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline, 5 g | sc-254228 | 5 g | $26.00 | |||
2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline, 25 g | sc-254228A | 25 g | $49.00 |