Date published: 2025-10-19

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Biotinyl Cystamine (CAS 128915-82-2)

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Application:
Biotinyl Cystamine is a crosslinking photoaffinity label ligand
CAS Number:
128915-82-2
Molecular Weight:
378.58
Molecular Formula:
C14H26N4O2S3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Biotinyl Cystamine, also referred to as BC, is a new form of cysteamine, an amino acid, that has been biotinylated. Biotinyl Cystamine is a compact compound specifically designed for scientific research purposes and has proven to be an invaluable asset in the investigation of various biological processes. Its applications encompass the examination of protein-protein interactions, protein-DNA interactions, as well as the exploration of biological pathway adjustments.The extensive utilization of Biotinyl Cystamine in scientific research spans diverse domains. It has played a role in unraveling protein-protein interactions, protein-DNA interactions, and the manipulation of biological pathways. Additionally, it has served as useful in scrutinizing cell signaling pathways related to inflammation, and the immune system. The examination of gene expression and the consequences of gene mutations have also benefited from the application of Biotinyl Cystamine. The binding properties of Biotinyl Cystamine, facilitated by its biotin component, offer an avenue to investigate protein-protein interactions. Moreover, the biotin moiety of Biotinyl Cystamine can form associations with DNA, enabling the study of protein-DNA interactions. Additionally, Biotinyl Cystamine has the capability to interact with enzymes, allowing for the examination of biological pathway modulation.


Biotinyl Cystamine (CAS 128915-82-2) References

  1. Sensitive and specific single-molecule sequencing of 5-hydroxymethylcytosine.  |  Song, CX., et al. 2011. Nat Methods. 9: 75-7. PMID: 22101853
  2. Mapping of O-GlcNAc sites of 20 S proteasome subunits and Hsp90 by a novel biotin-cystamine tag.  |  Overath, T., et al. 2012. Mol Cell Proteomics. 11: 467-77. PMID: 22556278
  3. Detection and identification of O-GlcNAcylated proteins by proteomic approaches.  |  Vercoutter-Edouart, AS., et al. 2015. Proteomics. 15: 1039-50. PMID: 25429863
  4. Fishing the PTM proteome with chemical approaches using functional solid phases.  |  Zhang, Y., et al. 2015. Chem Soc Rev. 44: 8260-87. PMID: 26258179
  5. Quantitative analysis of O-GlcNAcylation in combination with isobaric tag labeling and chemoenzymatic enrichment.  |  Tsumoto, H., et al. 2017. Bioorg Med Chem Lett. 27: 5022-5026. PMID: 29029932
  6. Covalently modified carboxyl side chains on cell surface leads to a novel method toward topology analysis of transmembrane proteins.  |  Müller, A., et al. 2019. Sci Rep. 9: 15729. PMID: 31673029

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Biotinyl Cystamine, 10 mg

sc-210924
10 mg
$320.00

Biotinyl Cystamine, 50 mg

sc-210924A
50 mg
$930.00