Molecular structure of Cyclophosphamide-d4, CAS Number: 173547-45-0
Cyclophosphamide-d4 (CAS 173547-45-0)
See product citations (13)
Alternate Names:
,N-Bis(2-chloroethyl)tetrahydro-4,5-d2-2H-1,3,2-oxazaphosphorin-2-amine 2-Oxide; Cycloblastin-d4;Cyclostin-d4
Application:
Cyclophosphamide-d4 is a DNA cross-linker
CAS Number:
173547-45-0
Purity:
≥98%
Molecular Weight:
265.11
Molecular Formula:
C7H11D4Cl2N2O2P
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Cyclophosphamide-d4 is a deuterated analog of cyclophosphamide, which is widely utilized in research that requires the precise quantification of cyclophosphamide through mass spectrometric techniques. Researchers employ Cyclophosphamide-d4 in kinetic studies to trace the absorption, distribution, metabolism, and excretion of cyclophosphamide in biological systems. Furthermore, it is used in the development and validation of sensitive analytical methods for detecting and quantifying cyclophosphamide in various matrices. This research contributes to a deeper understanding of the compound′s behavior in biological systems and is essential for the advancement of related scientific knowledge.
Cyclophosphamide-d4 (CAS 173547-45-0) References
- Synthesis of deuterium-labeled analogs of cyclophosphamide and its metabolites. | Griggs, LJ. and Jarman, M. 1975. J Med Chem. 18: 1102-6. PMID: 1177255
- The quantitation of cyclophosphamide in human blood and urine by mass spectrometry-stable isotope dilution. | Jarman, M., et al. 1975. Clin Chim Acta. 58: 61-9. PMID: 164304
- Sampling and mass spectrometric analytical methods for five antineoplastic drugs in the healthcare environment. | Pretty, JR., et al. 2012. J Oncol Pharm Pract. 18: 23-36. PMID: 21183556
- A surface wipe sampling and LC-MS/MS method for the simultaneous detection of six antineoplastic drugs commonly handled by healthcare workers. | Jeronimo, M., et al. 2015. Anal Bioanal Chem. 407: 7083-92. PMID: 26141324
- Ecotoxicity evaluation of a WWTP effluent treated by solar photo-Fenton at neutral pH in a raceway pond reactor. | Freitas, AM., et al. 2017. Environ Sci Pollut Res Int. 24: 1093-1104. PMID: 27335017
- Multi-channel cell co-culture for drug development based on glass microfluidic chip-mass spectrometry coupled platform. | Wu, J., et al. 2016. Rapid Commun Mass Spectrom. 30 Suppl 1: 80-6. PMID: 27539420
- Multicenter study of environmental contamination with cyclophosphamide, ifosfamide, and methotrexate in 66 Canadian hospitals: A 2016 follow-up study. | Roland, C., et al. 2017. J Occup Environ Hyg. 14: 661-669. PMID: 28574754
- Removal of contaminants of emerging concern by continuous flow solar photo-Fenton process at neutral pH in open reactors. | Arzate, S., et al. 2020. J Environ Manage. 261: 110265. PMID: 32148322
- Surface Contamination With Antineoplastic Drugs on Two Inpatient Oncology Units. | Walton, A., et al. 2020. Oncol Nurs Forum. 47: 263-272. PMID: 32301937
- Detection of anticancer drugs in wastewater effluents: Grab versus passive sampling. | Cristóvão, MB., et al. 2021. Sci Total Environ. 786: 147477. PMID: 33971591
- Are cytostatic drugs in surface waters a potential threat? | Gouveia, TIA., et al. 2022. Sci Total Environ. 853: 158559. PMID: 36087660
- Multi-target analysis of cytostatics in hospital effluents over a 9-month period. | Gouveia, TIA., et al. 2023. J Hazard Mater. 448: 130883. PMID: 36731320
- 5-Fluoro- and 5-chlorocyclophosphamide: synthesis, metabolism, and antitumor activity of the cis and trans isomers. | Foster, AB., et al. 1981. J Med Chem. 24: 1399-403. PMID: 7310816
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cyclophosphamide-d4, 1 mg | sc-211153 | 1 mg | $398.00 |