Gemin8 Activators
Gemin8 Activators represent a diverse class of chemicals that function primarily through indirect modulation of Gemin8. Most activators function by influencing signaling pathways that Gemin8 is involved in, notably the mTOR pathway. For example, they can activate the PI3K/AKT/mTOR pathway, which in turn regulate Gemin8. By stimulating this pathway, these activators can indirectly increase the translation of Gemin8. Similarly, activators can stimulate the AKT/mTOR pathway, thereby indirectly enhancing Gemin8 expression.
However, some activators, traditionally known as inhibitors of the mTOR pathway or PI3K, can paradoxically lead to a compensatory activation of these pathways under certain conditions. This can result in an indirect increase in Gemin8 expression. Gemin8 Activators function through different cellular pathways but can still indirectly influence the activity of Gemin8 through their interactions with the mTOR pathway. The activators can inhibit the V-ATPase, leading to mTOR activation, which could indirectly enhance Gemin8 expression.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $153.00 $1224.00 $12239.00 | 82 | |
Insulin is a potent activator of the PI3K/AKT/mTOR pathway. By stimulating this pathway, it can indirectly increase the translation of Gemin8. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Although traditionally considered an mTOR inhibitor, rapamycin can have a paradoxical effect of activating mTOR signaling under certain conditions, which can potentially increase Gemin8 expression. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C (PKC), which can stimulate the AKT/mTOR pathway and subsequently enhance Gemin8 expression. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor that can lead to a compensatory activation of the PI3K/AKT/mTOR pathway, which could indirectly enhance Gemin8 expression. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin increases intracellular cAMP levels, activating protein kinase A (PKA). PKA can stimulate the mTOR pathway, potentially increasing Gemin8 translation. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol has been shown to activate SIRT1, which can interact with the mTOR pathway. This interaction can potentially lead to an increase in Gemin8 expression. | ||||||
Metformin-d6, Hydrochloride | 1185166-01-1 | sc-218701 sc-218701A sc-218701B | 1 mg 5 mg 10 mg | $286.00 $806.00 $1510.00 | 1 | |
Metformin activates AMPK, which in turn can inhibit mTOR. This inhibition could lead to a compensatory activation of mTOR, potentially enhancing Gemin8 expression. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
AICAR activates AMPK, which can indirectly modulate mTOR activity, and subsequently Gemin8 expression. | ||||||
Bafilomycin A1 | 88899-55-2 | sc-201550 sc-201550A sc-201550B sc-201550C | 100 µg 1 mg 5 mg 10 mg | $96.00 $250.00 $750.00 $1428.00 | 280 | |
Bafilomycin A1 inhibits the V-ATPase, leading to mTOR activation. This activation could indirectly enhance Gemin8 expression. | ||||||
Torin 1 | 1222998-36-8 | sc-396760 | 10 mg | $240.00 | 7 | |
Torin 1 is an mTOR inhibitor that can lead to a compensatory activation of mTOR under certain conditions, potentially enhancing Gemin8 expression. | ||||||