G6PT Activators
The chemical class G6PT Activators encompasses compounds that indirectly influence the activity of G6PT by modulating various aspects of glucose metabolism. These compounds primarily act on pathways such as insulin signaling, glucose uptake, glycogen synthesis, and AMPK activation, which are crucial for the regulation of glucose homeostasis and glycogen storage, processes in which G6PT plays a significant role.
For instance, compounds like Metformin, Phenformin, and Berberine activate AMPK, a key regulator of cellular energy homeostasis. AMPK activation can lead to changes in glucose metabolism that might indirectly enhance G6PT activity by altering the demand for glucose-6-phosphate transport. Similarly, PPARγ agonists like Rosiglitazone and Pioglitazone modulate glucose uptake and utilization, which could influence the functional demand on G6PT. Additionally, compounds affecting insulin secretion and action, such as Glimepiride and Glibenclamide, as well as alpha-glucosidase inhibitors like Acarbose and Voglibose, can indirectly impact G6PT activity by modifying the cellular glucose environment. These effects are a result of the interconnected nature of glucose metabolism pathways, where changes in one aspect can affect various processes, including those mediated by G6PT.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $43.00 $63.00 $156.00 $260.00 $510.00 $31.00 | 37 | |
Metformin activates AMP-activated protein kinase (AMPK), which can influence glucose metabolism and potentially impact G6PT activity. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $120.00 $326.00 $634.00 $947.00 $1259.00 | 38 | |
As a PPARγ agonist, Rosiglitazone influences glucose uptake and metabolism, potentially affecting G6PT activity. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $55.00 $125.00 | 13 | |
Pioglitazone, a PPARγ agonist, modulates glucose metabolism, which could indirectly influence G6PT activity. | ||||||
D-Glucosamine | 3416-24-8 | sc-278917A sc-278917 | 1 g 10 g | $201.00 $779.00 | ||
Glucosamine affects glucose metabolism, which might indirectly influence G6PT activity. | ||||||
Acarbose | 56180-94-0 | sc-203492 sc-203492A | 1 g 5 g | $226.00 $605.00 | 1 | |
Acarbose inhibits intestinal alpha-glucosidases, altering glucose absorption and potentially impacting G6PT activity. | ||||||
Phenformin Hydrochloride | 834-28-6 | sc-219590 | 10 g | $119.00 | 4 | |
Phenformin activates AMPK, influencing glucose metabolism and potentially affecting G6PT activity. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine activates AMPK, which can modulate glucose metabolism and indirectly impact G6PT. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $65.00 $280.00 $400.00 | 48 | |
AICAR activates AMPK and influences glucose metabolism, potentially impacting G6PT activity. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
Insulin regulates glucose uptake and metabolism, potentially affecting G6PT activity indirectly. | ||||||
Glyburide (Glibenclamide) | 10238-21-8 | sc-200982 sc-200982A sc-200982D sc-200982B sc-200982C | 1 g 5 g 25 g 100 g 500 g | $46.00 $61.00 $117.00 $173.00 $530.00 | 36 | |
Glibenclamide, another sulfonylurea, can influence insulin secretion and potentially impact G6PT activity. | ||||||