Date published: 2026-5-13

1-800-457-3801

SCBT Portrait Logo
Seach Input

ERR beta Activators

Santa Cruz Biotechnology now offers a broad range of ERR beta Activators for use in various applications. ERR beta Activators target the Estrogen-Related Receptor beta (ERRβ), a lesser-known but crucial member of the nuclear receptor family, involved in the regulation of developmental and metabolic processes. These activators are used extensively in scientific research to explore the role of ERRβ in gene expression modulation and its impact on cellular function. By activating ERRβ, researchers can investigate its involvement in the transcriptional networks controlling developmental pathways and metabolic regulation, particularly in tissues where it is predominantly expressed. The application of ERR beta Activators has shed light on the intricate mechanisms through which this receptor influences cellular differentiation, energy homeostasis, and mitochondrial biogenesis without the influence of endogenous hormones. This research is critical for understanding the non-classical pathways that contribute to cellular development and metabolism, offering insights into how cells adapt to various metabolic demands and environmental stimuli. In addition, ERR beta Activators are vital for studies aiming to delineate the distinct roles of related receptors in the ERR family, providing a clearer picture of their individual contributions to cellular physiology. These activators thus play a pivotal role in advancing our comprehension of cellular regulation and the complex signaling networks. View detailed information on our available ERR beta Activators by clicking on the product name.

Items 1 to 10 of 14 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

GSK 4716

101574-65-6sc-203986
sc-203986A
10 mg
50 mg
$71.00
$285.00
(1)

GSK 4716 acts as a selective modulator of ERR beta, engaging in specific hydrogen bonding and hydrophobic interactions within the receptor's binding pocket. This compound influences ERR beta's conformational dynamics, resulting in altered gene transcription profiles. Its unique kinetic behavior suggests a non-competitive inhibition mechanism, impacting various metabolic pathways. GSK 4716's distinct binding characteristics provide a deeper understanding of ERR beta's role in cellular energy regulation and metabolic processes.

Pioglitazone hydrochloride

112529-15-4sc-204848
sc-204848A
100 mg
500 mg
$63.00
$213.00
19
(2)

Influences adipogenesis pathways interacting with ERRβ signaling, potentially affecting ERRβ activity indirectly.

DY131

95167-41-2sc-203571
sc-203571A
10 mg
50 mg
$132.00
$520.00
1
(1)

DY131 serves as a selective modulator of ERR beta, exhibiting unique binding affinity through intricate van der Waals interactions and electrostatic forces within the receptor's active site. This compound induces conformational shifts that enhance or inhibit specific transcriptional activities. Its kinetic profile indicates a potential allosteric modulation, influencing metabolic signaling pathways. DY131's distinct molecular interactions contribute to a nuanced understanding of ERR beta's regulatory functions in cellular metabolism.

1,1-Dimethylbiguanide, Hydrochloride

1115-70-4sc-202000F
sc-202000A
sc-202000B
sc-202000C
sc-202000D
sc-202000E
sc-202000
10 mg
5 g
10 g
50 g
100 g
250 g
1 g
$20.00
$43.00
$63.00
$156.00
$260.00
$510.00
$31.00
37
(1)

Activates AMPK, influencing metabolic pathways and potentially affecting ERRβ activity.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

Modulates mTOR pathway, potentially influencing ERRβ activity through effects on cellular metabolism and energy balance.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

Affects chromatin remodeling and gene expression, potentially altering ERRβ transcriptional activity.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Influences cell differentiation and development pathways, potentially affecting ERRβ's role.

Tamoxifen

10540-29-1sc-208414
2.5 g
$272.00
18
(2)

Influences ERRβ activity through cross-talk between ER and ERRβ signaling pathways.

GW 3965 hydrochloride

405911-17-3sc-224011
sc-224011A
sc-224011B
5 mg
25 mg
1 g
$140.00
$483.00
$3121.00
(1)

Impacts cholesterol metabolism, potentially affecting ERRβ activity in metabolic regulation.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$91.00
$139.00
$374.00
36
(1)

Modulates GR pathways, potentially affecting ERRβ activity in inflammatory and metabolic processes.