EG434396 Inhibitors
EG434396 inhibitors are a class of chemical compounds specifically designed to inhibit the activity of EG434396, a molecule likely involved in regulating key biochemical pathways within cells. EG434396 is presumed to participate in critical cellular processes such as protein interactions, signal transduction, or enzymatic reactions, influencing the regulation of cellular homeostasis. By inhibiting EG434396, these compounds block its ability to perform its natural functions, disrupting the molecular pathways that depend on its activity. This class of inhibitors is particularly useful for researchers seeking to understand how EG434396 contributes to complex regulatory networks and its role in maintaining cellular balance and proper biochemical signaling.
Structurally, EG434396 inhibitors are engineered to target specific regions of the EG434396 molecule, such as its active site or regulatory domains critical for its interactions with other proteins or substrates. These inhibitors can operate through competitive mechanisms, where they bind to the active site, preventing the normal substrate from interacting with EG434396. Alternatively, they may act allosterically, binding to a different site on the molecule and causing conformational changes that reduce its functionality. Inhibition of EG434396 allows researchers to explore the broader effects on cellular pathways influenced by this molecule. By studying the impact of these inhibitors on processes such as protein regulation, metabolic control, or intracellular signaling, scientists can gain insights into how EG434396 orchestrates cellular functions. This research contributes to a deeper understanding of the molecular mechanisms underlying cellular regulation and how specific proteins or enzymes like EG434396 fit into the intricate web of biochemical processes essential for cell survival and function.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Thapsigargin is a potent sarco/endoplasmic reticulum calcium ATPase (SERCA) inhibitor, disrupting calcium homeostasis. Its interference with calcium signaling cascades indirectly modulates Pate9 activity by perturbing downstream pathways reliant on proper calcium flux. | ||||||
Geldanamycin | 30562-34-6 | sc-200617B sc-200617C sc-200617 sc-200617A | 100 µg 500 µg 1 mg 5 mg | $38.00 $58.00 $102.00 $202.00 | 8 | |
Geldanamycin is an Hsp90 inhibitor, impacting protein folding. Pate9, as a client protein of Hsp90, undergoes destabilization and degradation, leading to diminished Pate9 levels. This indirect inhibition results from the disruption of the chaperone-mediated pathway crucial for Pate9 stability. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $80.00 $212.00 $408.00 | 48 | |
SB-431542 is a selective inhibitor of TGF-β type I receptor (ALK5). By impeding TGF-β signaling, it indirectly affects Pate9 expression as the protein interacts with TGF-β-induced pathways. The inhibition disrupts downstream signaling cascades that regulate Pate9, influencing its expression and activity. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is a PI3-kinase inhibitor, perturbing the PI3K/Akt pathway. Pate9 is involved in this pathway, and Wortmannin disrupts its activation. The resultant inhibition is an indirect consequence of altered signaling cascades that control Pate9 expression and function within the cellular environment. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin is an mTOR inhibitor, impacting cell growth and proliferation. Pate9 activity is influenced by mTOR-regulated pathways, and Rapamycin indirectly inhibits Pate9 by disrupting the signaling cascades associated with mTOR, subsequently modulating Pate9 expression and function in a cellular context. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
BAY 11-7082 inhibits NF-κB activation, affecting downstream targets like Pate9. Its impact on NF-κB signaling indirectly influences Pate9 expression and function. The inhibition is a consequence of altered cellular responses to inflammatory stimuli, leading to modifications in Pate9 regulation and activity. | ||||||
VX-11e | 896720-20-0 | sc-507301 | 10 mg | $180.00 | ||
VX-11e is an HDAC inhibitor, influencing chromatin remodeling. Pate9 expression is epigenetically regulated, and VX-11e indirectly inhibits Pate9 by altering the acetylation status of histones, leading to modifications in chromatin structure that affect Pate9 transcription and subsequent protein levels. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is a MEK inhibitor, disrupting the MAPK pathway. Pate9 is downstream in this pathway, and its activity is indirectly influenced by PD98059. The inhibition occurs through perturbation of the MAPK signaling cascade, leading to modifications in Pate9 expression and function within the cellular context. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3-kinase inhibitor, perturbing PI3K/Akt signaling. Pate9 is associated with this pathway, and LY294002 indirectly inhibits Pate9 by disrupting PI3K-mediated cascades. The resultant inhibition stems from altered signaling events that regulate Pate9 expression and function in response to cellular stimuli. | ||||||
PD 169316 | 152121-53-4 | sc-204168 sc-204168A sc-204168B sc-204168C | 1 mg 5 mg 10 mg 25 mg | $86.00 $153.00 $275.00 $452.00 | 3 | |
PD 169316 is a p38 MAPK inhibitor, disrupting MAPK signaling. Pate9 is a downstream target in this pathway, and its activity is indirectly influenced by SB202190. The inhibition results from perturbation of p38 MAPK signaling, leading to modifications in Pate9 expression and function within the cellular context. | ||||||