Chemical activators of EG232801 constitute a diverse group of compounds that can modulate cellular signaling pathways, resulting in the activation of EG232801. This category includes molecules that can influence intracellular calcium levels, such as ionophores, which can indirectly lead to the activation of EG232801 by altering the calcium-dependent signaling pathways within cells. Additionally, activators within this class are known to impact the activity of protein kinase C, a kinase that when activated can lead to a cascade of cellular events that may engage EG232801. The regulation of cyclic AMP levels by certain chemicals, through the activation of adenylate cyclase or modulation of its receptors, also falls under the activities of EG232801 activators. These actions can lead to changes in the cellular signaling environment, which in turn can activate EG232801.
The chemical class of EG232801 activators also includes inhibitors of specific signaling molecules such as tyrosine kinases, calcineurin, NF-κB, MEK, and mTOR. By inhibiting these molecules, the activators can cause alterations in the signaling networks that control the activation state of immune cells. For instance, inhibition of NF-κB, a key regulator of immune responses, can lead to changes that can activate EG232801. Similarly, targeting the MAPK/ERK pathway or the p38 MAP kinase pathway can also result in the activation of EG232801. These activators work by modifying the broader signaling landscape within which EG232801 operates, thereby influencing its state of activity. Each chemical in the class of EG232801 activators exerts its effects through distinct molecular mechanisms, but all converge on the common outcome of enabling the activation of EG232801.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C (PKC), which is involved in signaling pathways that could activate EG232801 by altering the cellular context in which EG232801 operates. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Ionomycin acts as a calcium ionophore, raising intracellular calcium levels, which could activate EG232801 by affecting various signaling pathways, modifying the activation state of immune cells. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
Cyclosporin A inhibits calcineurin, which could activate EG232801 by altering T-cell activation and cytokine production, potentially altering the immune response. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $56.00 $156.00 $270.00 $665.00 | 37 | |
PGE2 interacts with its receptors to modulate cyclic AMP levels and can influence inflammatory responses, which could activate EG232801 by altering the immune environment. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin can modulate NF-κB pathway activation, which plays a critical role in regulating immune responses, and could activate EG232801 by influencing the signaling context. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone is a glucocorticoid that can suppress inflammation and modulate immune responses, which could activate EG232801 by altering immune cell activation states. | ||||||
Imatinib mesylate | 220127-57-1 | sc-202180 sc-202180A | 25 mg 100 mg | $44.00 $109.00 | 61 | |
Imatinib Mesylate inhibits certain tyrosine kinases, which could activate EG232801 by affecting the activation of immune cells. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
BAY 11-7082 inhibits NF-κB activation, which could activate EG232801 by affecting immune cell activity and signaling pathways related to EG232801. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a p38 MAP kinase inhibitor that could activate EG232801 by modifying inflammatory responses and influencing the activation state of immune cells related to EG232801 signaling. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 is a MEK inhibitor that could activate EG232801 by affecting the MAPK/ERK pathway, potentially altering immune cell responses. | ||||||