EDG-5 Activators
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $165.00 $322.00 $570.00 $907.00 $1727.00 | 7 | |
D-erythro-Sphingosine-1-phosphate, an EDG-5 compound, exhibits unique molecular behavior through its sphingosine backbone, which allows for specific hydrogen bonding and hydrophobic interactions. This compound plays a crucial role in cellular signaling pathways, influencing lipid raft formation and membrane dynamics. Its structural conformation enables selective binding to receptors, impacting downstream signaling cascades. Additionally, its reactivity is marked by the ability to participate in phosphorylation reactions, affecting its stability and interaction with other biomolecules. | ||||||
FTY720 | 162359-56-0 | sc-202161 sc-202161A sc-202161B | 1 mg 5 mg 25 mg | $33.00 $77.00 $120.00 | 14 | |
FTY720 is phosphorylated in vivo to form FTY720-phosphate, which acts as a functional antagonist at the S1P1 receptor and may lead to compensatory upregulation of other S1P receptors, including EDG-5. | ||||||
FTY720 Phosphate | 402615-91-2 | sc-205332 sc-205332A | 1 mg 5 mg | $181.00 $825.00 | 6 | |
FTY720 Phosphate, as an EDG-5 compound, showcases distinctive molecular characteristics through its phosphate group, which enhances its solubility and reactivity. This compound engages in specific electrostatic interactions, facilitating its role in modulating lipid bilayer properties. Its unique conformation allows for selective interactions with various proteins, influencing cellular processes. The compound's kinetic profile is characterized by rapid phosphorylation, impacting its stability and reactivity in biological systems. | ||||||
FTY720 (S)-Phosphate | 402616-26-6 | sc-205331 sc-205331A | 500 µg 1 mg | $113.00 $218.00 | 3 | |
FTY720 (S)-Phosphate, classified as an EDG-5, exhibits remarkable molecular behavior due to its phosphate moiety, which significantly influences its hydrophilicity and reactivity. This compound participates in intricate hydrogen bonding and ionic interactions, altering membrane dynamics. Its structural flexibility enables it to adopt conformations that preferentially bind to target proteins, thereby affecting signaling pathways. The compound's reactivity is further enhanced by its rapid conversion in aqueous environments, leading to dynamic interactions within cellular matrices. | ||||||
SEW2871 | 256414-75-2 | sc-203251 sc-203251A | 5 mg 10 mg | $38.00 $53.00 | 1 | |
SEW2871 is a selective agonist of the S1P1 receptor, and its activity might lead to changes in the expression levels of other S1P receptors such as EDG-5 as part of a regulatory feedback mechanism. | ||||||
CYM-5442 | 1094042-01-9 | sc-211156 sc-211156A | 5 mg 25 mg | $267.00 $1120.00 | 1 | |
CYM-5442 is a selective S1P1 receptor agonist. Its binding to S1P1 might trigger compensatory mechanisms that result in the upregulation of EDG-5. | ||||||
VPC 23019 | 449173-19-7 | sc-362817 | 10 mg | $364.00 | 4 | |
VPC 23019 is an antagonist at S1P1 and S1P3 receptors. Blocking these receptors may lead to feedback mechanisms that alter the expression of EDG-5. | ||||||
JTE 013 | 383150-41-2 | sc-203615 | 10 mg | $195.00 | 5 | |
JTE-013 is a selective S1P2 receptor antagonist. By blocking S1P2, it might lead to changes in the expression of other S1P receptors, including EDG-5. | ||||||
2-undecyl-thiazolidine-4-carboxylic acid | 298186-80-8 | sc-220768 sc-220768A | 5 mg 10 mg | $88.00 $166.00 | ||
CAY10444 is an antagonist of the S1P4 receptor. Blocking S1P4 might result in compensatory changes in the expression of EDG-5. | ||||||
PF-543 | 1415562-82-1 | sc-507507 | 10 mg | $210.00 | ||
PF-543 inhibits sphingosine kinase 1 (SphK1), potentially leading to changes in S1P levels and consequently influencing EDG-5 expression. | ||||||