DUS3L Inhibitors
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Staurosporine is a potent kinase inhibitor that can inhibit protein kinases crucial for phosphorylation events. DUS3L's activity can be indirectly inhibited by staurosporine if it relies on kinase-mediated signaling for activation or stabilization within the cell. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin is a specific inhibitor of mTOR, a kinase that regulates cell growth and proliferation. Inhibition of mTOR by rapamycin can downregulate signaling pathways that are necessary for the post-translational modifications or localization of DUS3L. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $63.00 $92.00 $250.00 $485.00 $1035.00 $2141.00 | 69 | |
Cyclosporin A is an immunosuppressant that inhibits calcineurin. By inhibiting calcineurin, Cyclosporin A can prevent the dephosphorylation of transcription factors that regulate the expression of proteins interacting with DUS3L, indirectly reducing its functional activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a PI3K inhibitor, which prevents the activation of AKT, a kinase downstream of PI3K. Inhibition of the PI3K/AKT pathway can alter the phosphorylation status of proteins that could be involved in the proper functioning of DUS3L. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
U0126 is a specific inhibitor of MEK1/2, which are upstream of ERK in the MAPK pathway. ERK directly phosphorylates a variety of downstream proteins; if DUS3L relies on ERK-mediated phosphorylation for its function, U0126 could indirectly inhibit DUS3L's activity. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is another PI3K inhibitor that prevents AKT activation. Similar to LY294002, by blocking the PI3K/AKT pathway, wortmannin can hinder the phosphorylation of proteins that may be essential for DUS3L's functional activity. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is an inhibitor of JNK, which is part of the MAPK pathway. Inhibition of JNK can affect transcription factors and other signaling proteins that modulate the function of DUS3L, leading to its indirect inhibition. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 is a specific inhibitor of p38 MAPK. By inhibiting p38 MAPK, SB203580 can affect the activity of downstream proteins that regulate the stability and function of DUS3L. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A is a histone deacetylase inhibitor that changes chromatin structure and gene expression. This can alter the transcription of proteins that form a complex with DUS3L or that regulate its function, thus indirectly inhibiting DUS3L. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is a MEK inhibitor which, by inhibiting MEK, prevents the activation of ERK. This can decrease the phosphorylation of proteins that may be required for DUS3L's activity, thereby indirectly inhibiting DUS3L. | ||||||