DPP7 Activators
Dipeptidyl peptidase 7 (DPP7), also known as quiescent cell proline dipeptidase (QPP), is an enzyme that belongs to the family of serine proteases. It is distinct from other dipeptidyl peptidases in that it cleaves dipeptides from the N-terminus of polypeptides without a preference for proline in the penultimate position. DPP7 is widely expressed across different tissues, including the immune system, where it plays a role in lymphocyte activation and proliferation.
The enzyme is implicated in the metabolism of various bioactive peptides, influencing physiological processes such as pain sensation, immune response, and possibly blood pressure regulation. DPP7's activity is important for the maintenance of cellular homeostasis, particularly in the degradation of intracellular peptides during protein turnover.Mutations or altered expression of DPP7 have been associated with certain pathological conditions, although the full extent of its involvement in disease states is not fully understood. As a protease, DPP7 is a target for intervention; inhibitors of DPP7 could be used to modulate its activity in various diseases, including cancer and immune disorders.
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates PKC which could lead to transcriptional changes increasing DPP7 expression. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin raises cAMP levels, potentially enhancing DPP7 expression through cAMP response elements in its promoter. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid regulates gene expression and may upregulate DPP7 as part of cellular differentiation processes. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Vitamin D3 modulates gene expression and may influence DPP7 expression in immune or bone-related cells. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin affects various signaling pathways and could modulate DPP7 expression through its anti-inflammatory effects. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol may influence DPP7 expression through its interaction with signaling pathways involved in cellular stress response. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG may modulate enzymes involved in peptide metabolism, potentially influencing DPP7 expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium butyrate, as an HDAC inhibitor, can alter gene expression and potentially increase DPP7 levels. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium affects several signaling pathways and may upregulate DPP7 through mechanisms involving glycogen synthase kinase-3 (GSK-3) inhibition. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $55.00 $125.00 | 13 | |
As a PPAR-gamma agonist, pioglitazone may influence DPP7 expression through its effects on metabolism and inflammation. | ||||||