DIS3 Activators
The group of compounds that can influence the activity of DIS3 protein is diverse and intriguing. They come from various chemical classes and exhibit unique molecular mechanisms of action. Resveratrol, a natural phenol, and Curcumin, a diarylheptanoid, can influence the transcription of DIS3 via their impact on transcription-regulating proteins like SIRT1. Forskolin, another natural compound, can indirectly affect DIS3 activity by increasing cAMP levels, influencing various signaling cascades. Epigallocatechin gallate, a type of catechin, and Sulforaphane, an isothiocyanate, can modulate various signaling pathways, thereby potentially influencing DIS3 transcription.
Capsaicin can influence DIS3 activity through its effect on TRPV1 channels, which subsequently can influence multiple signaling cascades. Quercetin, a potent flavonoid, and Caffeine, a well-known stimulant, can also indirectly affect DIS3 activity by modulating various signaling molecules and pathways. Genistein, a prominent isoflavone, and Indole-3-carbinol, found in glucobrassicin, have potential to modulate the activity of DIS3 through their influence on various cellular signaling pathways. Luteolin, another flavone, and Piperine, an alkaloid, can also potentially modulate DIS3 activity through their broad impact on cellular signaling. This diverse group of compounds, despite their different origins and structures, share the potential to modulate DIS3 activity, either indirectly or directly. As our understanding of cellular signaling and gene transcription grows, so too does the potential to uncover the exact mechanisms through which these compounds influence DIS3 activity.
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol is a natural phenol found in several plants. It can influence SIRT1, a protein deacetylase involved in regulating nuclear transcription. Through SIRT1, Resveratrol can theoretically affect the transcription of various genes, including DIS3. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin is a natural compound found in the spice turmeric. It is known to modulate numerous signaling molecules, potentially including those that may regulate DIS3 transcription. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin is a labdane diterpene that activates adenylate cyclase, leading to increased cyclic AMP (cAMP) levels. cAMP influences various signaling pathways that may indirectly affect DIS3 activity. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG is a type of catechin found in green tea. It can modulate various signaling pathways and potentially influence DIS3 transcription. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane is an isothiocyanate found in cruciferous vegetables. It can activate the Nrf2 pathway, which may indirectly influence DIS3 activity. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $96.00 $160.00 $240.00 $405.00 | 26 | |
Capsaicin, the active component of chili peppers, can activate TRPV1 channels. This activation may subsequently influence various signaling cascades that could potentially affect DIS3 activity. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin is a plant flavonol from the flavonoid group of polyphenols. It's known to modulate numerous signaling molecules and may indirectly influence DIS3 activity. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Caffeine is a central nervous system stimulant. It's known to inhibit phosphodiesterases, leading to increased cAMP levels which could indirectly affect DIS3 activity. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein is a phytoestrogen and the main isoflavone found in soy products. It can modulate various signaling pathways and potentially influence DIS3 transcription. | ||||||
Indole-3-carbinol | 700-06-1 | sc-202662 sc-202662A sc-202662B sc-202662C sc-202662D | 1 g 5 g 100 g 250 g 1 kg | $39.00 $61.00 $146.00 $312.00 $1032.00 | 5 | |
I3C is found in the breakdown of glucobrassicin, found in cruciferous vegetables. It can modulate the AhR pathway, which may indirectly influence DIS3 activity. | ||||||