DDX31 Activators
DDX31 activators, as outlined, play a role in RNA metabolism, cellular energetics, and transcriptional landscapes. For example, Betulinic Acid, by enhancing ATP levels, can boost the RNA unwinding potential of DDX31, given DEAD-box helicase's dependency on ATP. Compounds such as db-cAMP and Forskolin lead to elevated cellular cAMP, thereby potentially triggering processes dependent on helicases. Similarly, the effects of AICAR on AMPK activity or the direct influence of D-ribose on RNA synthesis are likely to underline the necessity for RNA helicases.
DNA-damaging agents like Etoposide can indirectly raise the requirement for RNA repair mechanisms, implicating DDX31. Altering the transcriptional milieu with agents like Sulforaphane, BAY 11-7082, Daidzein, and Dimethyl Fumarate might demand heightened RNA helicase activity to maintain RNA fidelity in the face of altered gene expression. Such compounds serve as notable examples of how indirect modulators can impact the functions of proteins like DDX31, emphasizing the interwoven nature of cellular pathways and machinery.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Betulinic Acid | 472-15-1 | sc-200132 sc-200132A | 25 mg 100 mg | $117.00 $344.00 | 3 | |
Enhances cellular ATP levels, facilitating the potential RNA unwinding activity of DDX31 due to DEAD-box helicase's ATP dependence. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $47.00 $136.00 $492.00 $4552.00 | 74 | |
Elevates cAMP in cells, stimulating cellular processes that might be reliant on RNA helicases like DDX31. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $51.00 $231.00 $523.00 | 63 | |
Induces DNA damage, thereby indirectly heightening the requirement for RNA repair helicases. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $65.00 $280.00 $400.00 | 48 | |
Promotes AMPK activity, influencing RNA metabolism and possibly amplifying the need for RNA helicases like DDX31. | ||||||
D-(−)-Ribose | 50-69-1 | sc-221458 sc-221458A sc-221458B sc-221458C sc-221458D sc-221458E sc-221458F | 5 g 25 g 100 g 250 g 1 kg 5 kg 10 kg | $26.00 $58.00 $112.00 $235.00 $612.00 $1224.00 $2040.00 | 1 | |
Enhances RNA synthesis, which can elevate the demand for RNA helicase activity. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylate cyclase, increasing cAMP levels which may instigate helicase-dependent pathways. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Activates the Nrf2 pathway which can indirectly necessitate increased RNA helicase activity by altering gene transcription. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $62.00 $85.00 $356.00 | 155 | |
Inhibits NF-κB activation. Alterations in this pathway can change gene expression and indirectly increase RNA helicase function. | ||||||
Daidzein | 486-66-8 | sc-24001 sc-24001A sc-24001B | 100 mg 500 mg 5 g | $28.00 $79.00 $165.00 | 32 | |
Affects several signaling pathways and gene expressions, which can indirectly heighten the demand for RNA helicases. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Affects multiple cellular pathways including transcription factors, indirectly increasing the need for RNA helicases. | ||||||