Rsrp1, or arginine/serine-rich protein 1, is a crucial player in various structures, including the central nervous system, extraembryonic components, and the retina. This protein, encoded by the human RSRP1 gene, plays a vital role in cellular processes. The activation of Rsrp1 involves a complex interplay of signaling pathways and molecular interactions. Activation of Rsrp1 can be achieved through direct or indirect means. Direct activators, such as forskolin and lithium chloride, act on Rsrp1 itself or closely related pathways. Indirect activators, like trichostatin A and GSK343, modulate epigenetic mechanisms, influencing Rsrp1 expression. Additionally, compounds like SB203580 and BAY 11-7082 indirectly activate Rsrp1 by affecting downstream pathways, highlighting the intricate regulatory networks governing Rsrp1 activity.
These chemicals collectively demonstrate the diverse mechanisms through which Rsrp1 can be activated, shedding light on the intricate web of molecular interactions that govern its function in various cellular contexts. Understanding these activation pathways is crucial for unraveling the full potential and functional significance of Rsrp1 in cellular processes.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin, a polyphenol found in turmeric, can indirectly activate Rsrp1 by inhibiting the NF-κB pathway. This inhibition reduces the expression of SPRY4, a negative regulator of Rsrp1, resulting in enhanced Rsrp1 activity and downstream effects. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol, a natural compound in grapes, indirectly activates Rsrp1 by modulating the SIRT1 pathway. Activation of SIRT1 enhances Rsrp1 expression and function, contributing to increased cellular processes where Rsrp1 plays a crucial role. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A, a histone deacetylase inhibitor, influences epigenetic regulation to activate Rsrp1. By increasing histone acetylation, it promotes transcriptional activation of Rsrp1, leading to heightened expression and subsequent cellular effects. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin stimulates adenylate cyclase, increasing cAMP levels. Elevated cAMP activates PKA, which phosphorylates and activates Rsrp1, playing a role in enhanced Rsrp1 function. The cAMP/PKA pathway serves as an indirect activator of Rsrp1 in response to forskolin. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium chloride activates the Wnt/β-catenin pathway, indirectly influencing Rsrp1. Activation of Wnt/β-catenin enhances Rsrp1 expression and function, illustrating the interplay between different signaling pathways and their impact on the activity of target proteins. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580, a p38 MAPK inhibitor, indirectly activates Rsrp1 by suppressing the p38 MAPK pathway. Inhibition of p38 MAPK results in increased expression and function of Rsrp1, highlighting the intricate regulatory networks that govern Rsrp1 activity within cellular contexts. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
BAY 11-7082 inhibits NF-κB activation, indirectly promoting Rsrp1 activity. By suppressing NF-κB signaling, BAY 11-7082 decreases SPRY4 expression, a negative regulator of Rsrp1, leading to heightened Rsrp1 function and downstream effects within cellular processes. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $56.00 $156.00 $270.00 $665.00 | 37 | |
Prostaglandin E2 (PGE2) indirectly activates Rsrp1 by influencing the EP4 receptor. PGE2-EP4 signaling enhances Rsrp1 expression and activity, showcasing the involvement of prostaglandin-mediated pathways in modulating the function of Rsrp1 within various cellular contexts. | ||||||
GSK343 | 1346704-33-3 | sc-397025 sc-397025A | 5 mg 25 mg | $148.00 $452.00 | 1 | |
GSK343, a histone methyltransferase inhibitor, indirectly activates Rsrp1 through epigenetic regulation. By inhibiting histone methylation, GSK343 promotes the transcriptional activation of Rsrp1, resulting in increased expression and subsequent cellular effects mediated by Rsrp1. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002, a PI3K inhibitor, indirectly activates Rsrp1 by modulating the PI3K/Akt pathway. Inhibition of PI3K leads to enhanced Rsrp1 expression and function, providing insight into the intricate regulatory mechanisms governing Rsrp1 activity within cellular signaling networks. |