Date published: 2025-12-8

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CLK Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of CLK monoclonal antibodies for applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). CLK proteins are key regulators of alternative splicing and gene expression, making them central to understanding cellular processes and disease mechanisms. The role of CLK proteins extends to cell cycle regulation and stress response pathways, which has significant implications for cancer research and therapeutic development. CLK proteins influence multiple cellular pathways through their kinase activity, affecting RNA processing and protein synthesis. Understanding CLK protein function has led to important discoveries in developmental biology and disease progression. Researchers studying CLK-mediated signaling pathways rely on specific molecular tools to uncover new therapeutic targets. Recent studies have highlighted the importance of CLK proteins in neurodegenerative disorders and cancer development. Santa Cruz Biotechnology monoclonal antibodies for CLK research support scientists worldwide in their quest to advance medical breakthroughs and therapeutic innovations.

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CLK Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

CLK1 Antibody (F-12)

sc-515897mouse IgG2a κ78-134 (h)WB, IP, IF, ELISAm, r, h
3
(2)

CLK1/4 Antibody (A-4)

sc-515307mouse IgG2a κ202-227 (h)WB, IP, IF, ELISAh

new

(1)

CLK2 Antibody (F-4)

sc-393909mouse IgG1 κ70-97 (h)WB, IP, IF, ELISAm, r, h

new

(2)

CLK3 Antibody (D-10)

sc-365225mouse IgG1 κ211-241 (h)WB, IP, IF, IHC(P), ELISAm, r, h
3
(2)

CLK3 Antibody (4F12)

sc-134301mouse IgG2b κ36-136 (h)WB, IP, IF, IHC(P), ELISAm, r, h

new

(4)

CLK CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CLK1 CRISPR/Cas9 KO Plasmid (h)

sc-402793hGene KnockoutGFP0
(0)

CLK1 HDR Plasmid (h)

sc-402793-HDRhHomology Directed RepairPuromycin0
(0)

CLK1 Double Nickase Plasmid (h)

sc-402793-NIChGene KnockoutPuromycin0
(0)

CLK1 Double Nickase Plasmid (h2)

sc-402793-NIC-2hGene KnockoutPuromycin0
(0)

CLK1 CRISPR/Cas9 KO Plasmid (m)

sc-419688mGene KnockoutGFP0
(0)

CLK1 Double Nickase Plasmid (m)

sc-419688-NICmGene KnockoutPuromycin0
(0)

CLK1 Double Nickase Plasmid (m2)

sc-419688-NIC-2mGene KnockoutPuromycin0
(0)

CLK2 CRISPR/Cas9 KO Plasmid (h)

sc-403326hGene KnockoutGFP
1
(0)

CLK2 HDR Plasmid (h)

sc-403326-HDRhHomology Directed RepairPuromycin
1
(0)

CLK2 Double Nickase Plasmid (h)

sc-403326-NIChGene KnockoutPuromycin
1
(0)

CLK2 Double Nickase Plasmid (h2)

sc-403326-NIC-2hGene KnockoutPuromycin
1
(0)

CLK2 CRISPR/Cas9 KO Plasmid (m)

sc-419689mGene KnockoutGFP0
(0)

CLK2 HDR Plasmid (m)

sc-419689-HDRmHomology Directed RepairPuromycin0
(0)

CLK2 Double Nickase Plasmid (m)

sc-419689-NICmGene KnockoutPuromycin0
(0)

CLK2 Double Nickase Plasmid (m2)

sc-419689-NIC-2mGene KnockoutPuromycin0
(0)

CLK3 CRISPR/Cas9 KO Plasmid (h)

sc-408665hGene KnockoutGFP0
(0)

CLK3 HDR Plasmid (h)

sc-408665-HDRhHomology Directed RepairPuromycin0
(0)

CLK3 Double Nickase Plasmid (h)

sc-408665-NIChGene KnockoutPuromycin0
(0)

CLK3 Double Nickase Plasmid (h2)

sc-408665-NIC-2hGene KnockoutPuromycin0
(0)

CLK3 CRISPR/Cas9 KO Plasmid (m)

sc-430423mGene KnockoutGFP0
(0)

CLK3 HDR Plasmid (m)

sc-430423-HDRmHomology Directed RepairPuromycin0
(0)

CLK3 Double Nickase Plasmid (m)

sc-430423-NICmGene KnockoutPuromycin0
(0)

CLK3 Double Nickase Plasmid (m2)

sc-430423-NIC-2mGene KnockoutPuromycin0
(0)

CLK4 CRISPR/Cas9 KO Plasmid (h)

sc-404084hGene KnockoutGFP0
(0)

CLK4 HDR Plasmid (h)

sc-404084-HDRhHomology Directed RepairPuromycin0
(0)

CLK4 Double Nickase Plasmid (h)

sc-404084-NIChGene KnockoutPuromycin0
(0)

CLK4 Double Nickase Plasmid (h2)

sc-404084-NIC-2hGene KnockoutPuromycin0
(0)

CLK4 CRISPR/Cas9 KO Plasmid (m)

sc-419690mGene KnockoutGFP0
(0)

CLK4 Double Nickase Plasmid (m)

sc-419690-NICmGene KnockoutPuromycin0
(0)

CLK4 Double Nickase Plasmid (m2)

sc-419690-NIC-2mGene KnockoutPuromycin0
(0)

CLK CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CLK1 CRISPR Activation Plasmid (h)

sc-402793-ACThGene ActivationPuro, Blast, Hygro0
(0)

CLK1 CRISPR Activation Plasmid (h2)

sc-402793-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

CLK1 Lentiviral Activation Particles (h)

sc-402793-LAChGene ActivationPuro, Blast, Hygro0
(0)

CLK1 Lentiviral Activation Particles (h2)

sc-402793-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

CLK1 CRISPR Activation Plasmid (m)

sc-419688-ACTmGene ActivationPuro, Blast, Hygro0
(0)

CLK1 CRISPR Activation Plasmid (m2)

sc-419688-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

CLK1 Lentiviral Activation Particles (m)

sc-419688-LACmGene ActivationPuro, Blast, Hygro0
(0)

CLK1 Lentiviral Activation Particles (m2)

sc-419688-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

CLK2 CRISPR Activation Plasmid (h)

sc-403326-ACThGene ActivationPuro, Blast, Hygro
1
(0)

CLK2 CRISPR Activation Plasmid (h2)

sc-403326-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

CLK2 Lentiviral Activation Particles (h)

sc-403326-LAChGene ActivationPuro, Blast, Hygro
1
(0)

CLK2 Lentiviral Activation Particles (h2)

sc-403326-LAC-2hGene ActivationPuro, Blast, Hygro
1
(0)

CLK2 CRISPR Activation Plasmid (m)

sc-419689-ACTmGene ActivationPuro, Blast, Hygro0
(0)

CLK2 CRISPR Activation Plasmid (m2)

sc-419689-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

CLK2 Lentiviral Activation Particles (m)

sc-419689-LACmGene ActivationPuro, Blast, Hygro0
(0)

CLK2 Lentiviral Activation Particles (m2)

sc-419689-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

CLK3 CRISPR Activation Plasmid (h)

sc-408665-ACThGene ActivationPuro, Blast, Hygro0
(0)

CLK3 CRISPR Activation Plasmid (h2)

sc-408665-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

CLK3 Lentiviral Activation Particles (h)

sc-408665-LAChGene ActivationPuro, Blast, Hygro0
(0)

CLK3 Lentiviral Activation Particles (h2)

sc-408665-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

CLK3 CRISPR Activation Plasmid (m)

sc-430423-ACTmGene ActivationPuro, Blast, Hygro0
(0)

CLK3 CRISPR Activation Plasmid (m2)

sc-430423-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

CLK3 Lentiviral Activation Particles (m)

sc-430423-LACmGene ActivationPuro, Blast, Hygro0
(0)

CLK3 Lentiviral Activation Particles (m2)

sc-430423-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

CLK4 CRISPR Activation Plasmid (h)

sc-404084-ACThGene ActivationPuro, Blast, Hygro0
(0)

CLK4 CRISPR Activation Plasmid (h2)

sc-404084-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

CLK4 Lentiviral Activation Particles (h)

sc-404084-LAChGene ActivationPuro, Blast, Hygro0
(0)

CLK4 Lentiviral Activation Particles (h2)

sc-404084-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

CLK4 CRISPR Activation Plasmid (m)

sc-419690-ACTmGene ActivationPuro, Blast, Hygro0
(0)

CLK4 CRISPR Activation Plasmid (m2)

sc-419690-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

CLK4 Lentiviral Activation Particles (m)

sc-419690-LACmGene ActivationPuro, Blast, Hygro0
(0)

CLK4 Lentiviral Activation Particles (m2)

sc-419690-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

CLK siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CLK1 siRNA (h)

sc-60404hGene SilencingN/A
2
(0)

CLK1 shRNA Plasmid (h)

sc-60404-SHhGene SilencingPuromycin
2
(0)

CLK1 shRNA (h) Lentiviral Particles

sc-60404-VhGene SilencingPuromycin
2
(0)

CLK1 siRNA (m)

sc-60405mGene SilencingN/A0
(0)

CLK1 shRNA Plasmid (m)

sc-60405-SHmGene SilencingPuromycin0
(0)

CLK1 shRNA (m) Lentiviral Particles

sc-60405-VmGene SilencingPuromycin0
(0)

CLK2 siRNA (h)

sc-72923hGene SilencingN/A
1
(0)

CLK2 shRNA Plasmid (h)

sc-72923-SHhGene SilencingPuromycin
1
(0)

CLK2 shRNA (h) Lentiviral Particles

sc-72923-VhGene SilencingPuromycin
1
(0)

CLK2 siRNA (m)

sc-72924mGene SilencingN/A0
(0)

CLK2 shRNA Plasmid (m)

sc-72924-SHmGene SilencingPuromycin0
(0)

CLK2 shRNA (m) Lentiviral Particles

sc-72924-VmGene SilencingPuromycin0
(0)

CLK3 siRNA (h)

sc-72925hGene SilencingN/A
1
(0)

CLK3 shRNA Plasmid (h)

sc-72925-SHhGene SilencingPuromycin
1
(0)

CLK3 shRNA (h) Lentiviral Particles

sc-72925-VhGene SilencingPuromycin
1
(0)

CLK3 siRNA (m)

sc-72926mGene SilencingN/A0
(0)

CLK3 shRNA Plasmid (m)

sc-72926-SHmGene SilencingPuromycin0
(0)

CLK3 shRNA (m) Lentiviral Particles

sc-72926-VmGene SilencingPuromycin0
(0)

CLK4 siRNA (h)

sc-105214hGene SilencingN/A
1
(0)

CLK4 shRNA Plasmid (h)

sc-105214-SHhGene SilencingPuromycin
1
(0)

CLK4 shRNA (h) Lentiviral Particles

sc-105214-VhGene SilencingPuromycin
1
(0)

CLK4 siRNA (m)

sc-142394mGene SilencingN/A0
(0)

CLK4 shRNA Plasmid (m)

sc-142394-SHmGene SilencingPuromycin0
(0)

CLK4 shRNA (m) Lentiviral Particles

sc-142394-VmGene SilencingPuromycin0
(0)