CIDE-C Inhibitors
CIDE-C inhibitors belong to a class of compounds that specifically target and modulate cellular functions associated with cell death-inducing DFF45-like effector C (CIDE-C) proteins. CIDE-C is a member of the CIDE family, which plays a crucial role in regulating apoptosis and lipid metabolism. These inhibitors are designed to interfere with the normal activity of CIDE-C, thus influencing cellular processes related to cell death and lipid homeostasis. The CIDE-C protein is primarily expressed in adipose tissue and has been implicated in adipocyte apoptosis and lipid droplet fusion. The development of CIDE-C inhibitors represents a significant advancement in the field of molecular biology, offering researchers a tool to selectively manipulate the functions governed by CIDE-C.
CIDE-C inhibitors often possess a specific chemical scaffold tailored to interact with the active site or binding pocket of the CIDE-C protein, disrupting its normal physiological functions. The design of these inhibitors is grounded in a deep understanding of the molecular interactions between CIDE-C and its cellular targets. By inhibiting CIDE-C, these compounds unveil novel insights into the intricate regulatory networks controlling cellular processes related to apoptosis and lipid metabolism. The study and utilization of CIDE-C inhibitors contribute to the broader understanding of cellular biology, offering researchers a valuable tool to dissect the molecular pathways associated with cell death and lipid homeostasis.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Triacsin C Solution in DMSO | 76896-80-5 | sc-200574 sc-200574A | 100 µg 1 mg | $187.00 $843.00 | 14 | |
Inhibits ACSLs, enzymes that activate fatty acids, thus potentially reducing CIDE-C activity by limiting substrate availability for lipid droplet formation. | ||||||
(+)-Etomoxir sodium salt | 828934-41-4 | sc-215009 sc-215009A | 5 mg 25 mg | $151.00 $506.00 | 3 | |
Blocks CPT1, reducing fatty acid transport into mitochondria, potentially affecting CIDE-C-related lipid metabolism. | ||||||
TOFA (5-(Tetradecyloxy)-2-furoic acid) | 54857-86-2 | sc-200653 sc-200653A | 10 mg 50 mg | $97.00 $374.00 | 15 | |
Inhibits ACC, leading to reduced fatty acid synthesis, indirectly affecting CIDE-C function. | ||||||
C75 (racemic) | 191282-48-1 | sc-202511 sc-202511A sc-202511B | 1 mg 5 mg 10 mg | $72.00 $206.00 $290.00 | 9 | |
Inhibits FAS, altering lipid metabolism and potentially influencing CIDE-C activity. | ||||||
Cerulenin (synthetic) | 17397-89-6 | sc-200827 sc-200827A sc-200827B | 5 mg 10 mg 50 mg | $161.00 $312.00 $1210.00 | 9 | |
Inhibits FAS, potentially affecting lipid droplet formation and CIDE-C activity. | ||||||
Betulinic Acid | 472-15-1 | sc-200132 sc-200132A | 25 mg 100 mg | $117.00 $344.00 | 3 | |
Inhibits stearoyl-CoA desaturase, which may affect lipid composition and influence CIDE-C function. | ||||||
rac Perhexiline Maleate | 6724-53-4 | sc-460183 | 10 mg | $188.00 | ||
Inhibits CPT1, potentially influencing CIDE-C through alterations in lipid metabolism. | ||||||
Niclosamide | 50-65-7 | sc-250564 sc-250564A sc-250564B sc-250564C sc-250564D sc-250564E | 100 mg 1 g 10 g 100 g 1 kg 5 kg | $38.00 $79.00 $188.00 $520.00 $1248.00 $5930.00 | 8 | |
Uncouples mitochondrial oxidative phosphorylation, which can indirectly affect energy metabolism and possibly influence CIDE-C activity. | ||||||
Simvastatin | 79902-63-9 | sc-200829 sc-200829A sc-200829B sc-200829C | 50 mg 250 mg 1 g 5 g | $31.00 $89.00 $135.00 $443.00 | 13 | |
Inhibits HMG-CoA reductase, leading to reduced cholesterol synthesis, which could indirectly affect CIDE-C activity. | ||||||
Lipase Inhibitor, THL | 96829-58-2 | sc-203108 | 50 mg | $52.00 | 7 | |
Inhibits gastrointestinal lipases, potentially affecting lipid absorption and indirectly CIDE-C function. | ||||||