Cerebellin 1 activators are a distinct group of compounds that aim to enhance the biological function of cerebellin 1, a neuropeptide that exerts significant influence on synaptic plasticity and neuronal communication within the brain. As an activator of cerebellin 1, these compounds specifically increase its interaction with its receptors, which are part of the complex signaling networks within the nervous system. The activation of cerebellin 1 has the potential to modulate the efficacy of synaptic transmission and influence the processes governing learning and memory. The compounds that serve as cerebellin 1 activators are of considerable interest in the field of neurobiology, where they are used to probe the role of cerebellin 1 in the fine-tuning of neurotransmitter release and in the regulation of synaptic functions across various neuronal populations.
The search for and characterization of cerebellin 1 activators involve elaborate research methodologies that blend chemistry with advanced biological assays. Initial stages might include the use of compound libraries to identify molecules with the potential to bind and activate cerebellin 1 or its receptors. Lead compounds identified through such high-throughput screening processes can then undergo further chemical modification to improve their potency, specificity, and selectivity as activators. Additionally, computational techniques such as molecular modeling and docking studies can help predict how these molecules interact at the atomic level with cerebellin 1 or its receptors, allowing for rational design improvements.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid plays a role in cell differentiation and development. It might upregulate CBLN1 expression as part of its role in promoting neuronal development. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin increases intracellular levels of cAMP, which can lead to the activation of protein kinase A (PKA) and potentially upregulate the expression of CBLN1. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 18 | |
Sodium butyrate is a histone deacetylase inhibitor that can enhance gene expression by altering chromatin structure. This might elevate CBLN1 expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A is another histone deacetylase inhibitor that might enhance CBLN1 expression by altering chromatin structure. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
5-Aza-2′-Deoxycytidine is a DNA methyltransferase inhibitor that can enhance gene expression by altering DNA methylation patterns. It might potentially induce CBLN1 expression. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein is a tyrosine kinase inhibitor and phytoestrogen that can modulate gene expression. It could potentially upregulate CBLN1 as part of its broader impacts on cellular processes. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol is known to have a variety of effects on cellular processes, including gene expression. It might upregulate CBLN1 expression as part of its broader impacts on cellular processes. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
DL-Sulforaphane is known to affect a variety of cellular processes, including gene expression. It might upregulate CBLN1 expression as part of its broader impacts on cellular processes. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $45.00 $130.00 $480.00 $4450.00 | 74 | |
dbcAMP is a cell-permeable cAMP analog. It can activate protein kinase A (PKA) and potentially upregulate the expression of CBLN1. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
(-)-Epigallocatechin Gallate, a polyphenol in green tea, has been shown to affect gene expression. It could potentially upregulate CBLN1 as part of its broader impacts on cellular processes. |