CD84 Activators
CD84 activators, in the context of this discussion, primarily encompass chemicals that indirectly influence CD84's activity by modulating signaling pathways and cellular processes relevant to CD84's role in immune regulation. These activators, rather than binding directly to CD84, exert their effects on various intracellular signaling cascades that can alter the functional state of CD84 or its expression levels.
The primary mode of action for these activators involves the modulation of kinases and other enzymes critical to cell signaling. For instance, compounds like Forskolin, U0126, and SP600125 target key enzymes like adenylate cyclase, MEK, and JNK, respectively. These enzymes play pivotal roles in the regulation of immune responses and can indirectly influence CD84-mediated pathways. Similarly, agents like Rapamycin and Cyclosporin A, known for their roles in immunosuppression, can alter cellular environments, indirectly affecting CD84's functional dynamics.
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA is known to activate Protein Kinase C (PKC), which can influence various immune cell functions, potentially affecting CD84 signaling indirectly. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Ionomycin is a calcium ionophore that increases intracellular calcium levels, possibly impacting CD84-mediated signaling in immune cells. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cAMP levels, which may indirectly influence CD84 activity in immune cells. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $62.00 $85.00 $356.00 | 155 | |
This compound inhibits NF-κB, a factor in immune response regulation, potentially affecting CD84 signaling pathways. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of JNK, SP600125 might indirectly affect CD84 signaling by modulating JNK-dependent pathways in immune cells. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
This p38 MAPK inhibitor could potentially influence CD84 signaling pathways indirectly. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K inhibitor, LY294002 can affect various signaling pathways, possibly intersecting with CD84-related processes. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
As an mTOR inhibitor, Rapamycin could indirectly influence CD84 signaling through its regulatory roles in immune responses. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $63.00 $92.00 $250.00 $485.00 $1035.00 $2141.00 | 69 | |
Known for its immunosuppressive properties, it could indirectly affect CD84 activity by modulating immune cell functions. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
An ERK inhibitor that might indirectly affect CD84 signaling pathways in immune cells. | ||||||