caspase-9 Inhibitors
SEE ALSO...
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Q-VD-OPH | 1135695-98-5 | sc-222230 | 5 mg | $782.00 | 5 | |
Q-VD-OPh is a broad-spectrum caspase inhibitor. It can inhibit caspase-9 activity, preventing downstream apoptotic events. | ||||||
caspase-9 inhibitor I | 210345-04-3 | sc-3085 sc-3085A | 1 mg 5 mg | $416.00 $1769.00 | 33 | |
caspase-9 inhibitor I is a cell-permeable, irreversible caspase-9 inhibitor. It binds to the active site of caspase-9, preventing its proteolytic activity. | ||||||
Caspase-9 Inhibitor III | 403848-57-7 | sc-300327 sc-300327A | 1 mg 5 mg | $152.00 $474.00 | 6 | |
Caspase-9 Inhibitor III exhibits a selective binding affinity for the active site of caspase-9, disrupting its proteolytic function. This inhibitor alters the enzyme's conformational dynamics, leading to a decrease in its catalytic turnover rate. By forming stable complexes with key residues, it effectively hinders substrate access, thereby modulating apoptotic signaling cascades. Its unique structural features allow for specific interactions that finely tune caspase-9 activity. | ||||||
Emricasan | 254750-02-2 | sc-507387 | 5 mg | $90.00 | ||
Emricasan is a pan-caspase inhibitor. It can inhibit caspase-9, among other caspases, preventing apoptosis. | ||||||
caspase-9 inhibitor II | sc-3086 | 1 mg | $364.00 | 1 | ||
Caspase-9 Inhibitor II is characterized by its ability to engage in non-covalent interactions with the caspase-9 enzyme, effectively stabilizing an inactive conformation. This inhibitor influences the enzyme's allosteric sites, resulting in altered substrate binding kinetics. Its distinct molecular architecture facilitates selective interactions that prevent the activation of downstream apoptotic pathways, thereby providing a nuanced modulation of cellular signaling mechanisms. | ||||||
Apoptosis Inhibitor | 54135-60-3 | sc-205595 | 10 mg | $160.00 | 1 | |
Apoptosis Inhibitor is a specific caspase-9 inhibitor. It binds to and inhibits the proteolytic activity of caspase-9. | ||||||
Caspase-8 inhibitor II | 210344-98-2 | sc-3084 sc-3084A | 1 mg 3 mg | $291.00 $624.00 | 48 | |
While Caspase-8 inhibitor II is primarily a caspase-8 inhibitor, it might also influence caspase-9 activity under certain conditions. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $63.00 $182.00 | 8 | |
Estrogen can exhibit neuroprotective effects and inhibit apoptosis by potentially affecting caspase-9 activation. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol, a polyphenol, has been shown to inhibit apoptosis in various models, potentially by affecting caspase-9 activation. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, a component of green tea, can inhibit apoptosis in certain settings, potentially by affecting caspase-9 activation. | ||||||