Date published: 2026-2-13

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Apoptosis Inhibitor (CAS 54135-60-3)

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Alternate Names:
2,2′-Methylenebis(1,3-cyclohexanedione)
Application:
Apoptosis Inhibitor is a cell-permeable inhibitor of apoptosis induction
CAS Number:
54135-60-3
Purity:
≥95%
Molecular Weight:
236.3
Molecular Formula:
C13H16O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Apoptosis Inhibitor is a chemical compound that holds significant interest in scientific research due to its potential applications across various domains. The precise mechanism of action employed by Apoptosis Inhibitor remains partially understood. However, current understanding suggests that it functions by inhibiting specific enzymes involved in cell growth and division.


Apoptosis Inhibitor (CAS 54135-60-3) References

  1. Inhibitory effect of M50054, a novel inhibitor of apoptosis, on anti-Fas-antibody-induced hepatitis and chemotherapy-induced alopecia.  |  Tsuda, T., et al. 2001. Eur J Pharmacol. 433: 37-45. PMID: 11755132
  2. Compounds blocking mutant huntingtin toxicity identified using a Huntington's disease neuronal cell model.  |  Wang, W., et al. 2005. Neurobiol Dis. 20: 500-8. PMID: 15908226
  3. Apoptosis is required during early stages of tail regeneration in Xenopus laevis.  |  Tseng, AS., et al. 2007. Dev Biol. 301: 62-9. PMID: 17150209
  4. Inhibition of caspase-3-mediated apoptosis improves spinal cord repair in a regeneration-competent vertebrate system.  |  Sîrbulescu, RF. and Zupanc, GK. 2010. Neuroscience. 171: 599-612. PMID: 20837106
  5. Adult neurogenesis and neuronal regeneration in the central nervous system of teleost fish.  |  Zupanc, GK. and Sîrbulescu, RF. 2011. Eur J Neurosci. 34: 917-29. PMID: 21929625
  6. Teleost fish as a model system to study successful regeneration of the central nervous system.  |  Zupanc, GK. and Sîrbulescu, RF. 2013. Curr Top Microbiol Immunol. 367: 193-233. PMID: 23239273
  7. An Optimal Medium Supplementation Regimen for Initiation of Hepatocyte Differentiation in Human Induced Pluripotent Stem Cells.  |  Tomizawa, M., et al. 2015. J Cell Biochem. 116: 1479-89. PMID: 25683148
  8. Improved Survival and Initiation of Differentiation of Human Induced Pluripotent Stem Cells to Hepatocyte-Like Cells upon Culture in William's E Medium followed by Hepatocyte Differentiation Inducer Treatment.  |  Tomizawa, M., et al. 2016. PLoS One. 11: e0153435. PMID: 27073925
  9. 2‑Deoxy‑D‑glucose initiates hepatocyte differentiation in human induced pluripotent stem cells.  |  Tomizawa, M., et al. 2017. Mol Med Rep. 15: 3083-3087. PMID: 28358426
  10. Innovation for hepatotoxicity in vitro research models: A review.  |  Han, W., et al. 2019. J Appl Toxicol. 39: 146-162. PMID: 30182494

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Apoptosis Inhibitor, 10 mg

sc-205595
10 mg
$160.00