CAD Activators
The chemical class of CAD Activators includes compounds that can indirectly influence CAD function through their effects on apoptosis and DNA damage pathways. CAD is activated during the late stages of apoptosis, particularly in response to apoptotic signals and DNA damage. Compounds such as Staurosporine, Etoposide, Camptothecin, and Doxorubicin are known to induce apoptosis through various mechanisms, including kinase inhibition and DNA damage induction. The initiation of apoptosis by these compounds can lead to the activation of caspases, which in turn activate CAD.
Chemotherapy drugs like Cisplatin and Actinomycin D, as well as microtubule-targeting agents such as Vinblastine and Paclitaxel, can induce apoptosis, potentially leading to the activation of CAD. These compounds induce DNA damage or disrupt cellular structures, triggering apoptotic pathways that involve CAD. Furthermore, natural compounds with apoptotic properties like Sulforaphane, Curcumin, and Resveratrol could also indirectly influence CAD activation. These compounds are known to modulate apoptotic pathways in various cell types, which could lead to the activation of CAD.
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A potent kinase inhibitor, can induce apoptosis, potentially affecting CAD activation indirectly. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
Induces DNA damage, leading to apoptosis and potentially influencing CAD activation. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
An inhibitor of DNA topoisomerase I, induces apoptosis, possibly affecting CAD activity. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Inhibits protein synthesis, leading to apoptosis and potentially affecting CAD activation. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $173.00 $418.00 | 43 | |
An anthracycline antibiotic, induces DNA damage and apoptosis, potentially impacting CAD activation. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $76.00 $216.00 | 101 | |
A chemotherapy drug, induces DNA damage and apoptosis, possibly influencing CAD activation. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Inhibits RNA synthesis, leading to apoptosis, potentially affecting CAD activity. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $100.00 $230.00 $450.00 $1715.00 $2900.00 | 4 | |
Disrupts microtubule formation, leading to apoptosis, which could indirectly activate CAD. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Stabilizes microtubules, inducing apoptosis, potentially impacting CAD activation. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Found in cruciferous vegetables, induces apoptosis in certain cell types, possibly influencing CAD. | ||||||