C5orf40 Activators
5orf40 activators encompass a range of compounds that enhance the functional activity of this fibronectin type III domain-containing protein through various intracellular signaling pathways. For instance, certain agents directly stimulate adenylyl cyclase or serve as cAMP analogs, leading to a rise in intracellular cAMP levels. This elevation in cAMP is crucial as it initiates a cascade of signaling events that ultimately converge on the regulation of fibronectin type III domain proteins, including C5orf40. Similarly, other molecules function by inhibiting the breakdown of cAMP, thereby indirectly supporting the persistent activation of these proteins. Additionally, some activators operate by increasing intracellular calcium concentrations, either through ionophoretic mechanisms or activation of receptors that triggercalcium influx. These fluctuations in calcium levels activate calcium-dependent kinases, which are known to regulate the activity of proteins like C5orf40 by affecting cellular adhesion and cytoskeletal dynamics.
Moreover, various activators exert their influence by engaging with specific receptor-mediated pathways. For example, compounds that activate adrenergic or glucagon receptors amplify the production of cAMP, thus indirectly promoting the activation of C5orf40 within its associated signaling networks. Other activators interact with the insulin signaling pathway, which through a series of downstream effects, can modulate the functional state of C5orf40. This modulation is particularly relevant in the context of cellular processes governed by fibronectin type III domain-containing proteins. Additionally, there are activators that target protein kinase C, which is a key player in numerous signaling pathways that dictate the dynamics of cellular adhesion structures. Activation of protein kinase C leads to downstream signaling events that are capable of influencing the activation status of C5orf40.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
Non-specific inhibitor of phosphodiesterases, which prevents the breakdown of cAMP. By sustaining cAMP levels, it indirectly supports the activation of C5orf40, as cAMP is a messenger in pathways that influence the function of fibronectin type III domain-containing proteins. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Direct activator of protein kinase C (PKC) which is involved in a multitude of signaling pathways. PKC activation can lead to downstream signaling events that promote the activation of C5orf40, as PKC modulates the dynamics of the cytoskeleton and cellular adhesion where fibronectin type III domain-containing proteins are crucial. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
Calcium ionophore that increases intracellular calcium levels, influencing signaling pathways that regulate the function of fibronectin type III domain-containing proteins, including C5orf40. Increased calcium may activate calcium-dependent kinases that modulate the activity of C5orf40. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $40.00 $102.00 $197.00 $1739.00 $16325.00 | ||
Activates adrenergic receptors, leading to increased cAMP production. The cAMP signaling pathway can subsequently activate C5orf40 through secondary messenger cascades that affect fibronectin type III domain-containing proteins. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $153.00 $1224.00 $12239.00 | 82 | |
Activates the insulin receptor, leading to downstream signaling via the PI3K/Akt pathway. This pathway can regulate cellular processes that involve fibronectin type III domain-containing proteins like C5orf40, potentially affecting its activation status. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
A calcium ionophore that raises intracellular calcium levels, which may trigger signaling pathways that impact the function of C5orf40 by modulating the cellular adhesion and cytoskeletal dynamics where fibronectin type III domains play a role. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $45.00 $130.00 $480.00 $4450.00 | 74 | |
A cAMP analog that is resistant to degradation by phosphodiesterases. This compound can maintain elevated cAMP levels, indirectly facilitating the activation of C5orf40 as part of signaling processes that involve fibronectin type III domain-containing proteins. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $75.00 $212.00 | 18 | |
Selective inhibitor of phosphodiesterase 4 (PDE4), which increases intracellular cAMP levels. This can indirectly lead to the activation of C5orf40 by modulating signaling pathways associated with the function of fibronectin type III domain-containing proteins. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $27.00 $37.00 | 5 | |
A synthetic beta-adrenergic receptor agonist that elevates intracellular cAMP levels. The increased cAMP can indirectly activate C5orf40 by influencing pathways that regulate fibronectin type III domain-containing proteins. | ||||||
Glucagon trifluoroacetic acid salt | 9007-92-5 (free base) | sc-495801 | 1 mg | $480.00 | ||
Activates glucagon receptors leading to increased cAMP production. The elevated cAMP levels can contribute to the activation of C5orf40 through signaling pathways that involve fibronectin type III domain-containing proteins. | ||||||