C2orf49_AI597479 Activators
AI597479, an expressed sequence predicted to be involved in embryonic morphogenesis and part of the tRNA-splicing ligase complex, plays a pivotal role in the intricate processes governing early development. As an integral member of the ligase complex, AI597479 is anticipated to contribute to the splicing of tRNA molecules, a crucial step in the synthesis of functional transfer RNAs. The predicted localization of AI597479 in the nucleus aligns with its putative role in transcriptional regulation, suggesting its involvement in shaping the transcriptional landscape during embryonic development. Furthermore, the orthology with human C2orf49 hints at potential conservation of function across species, emphasizing the evolutionary significance of AI597479 in fundamental biological processes.
The activation of AI597479 involves a sophisticated interplay of various cellular mechanisms, each contributing to its enhanced expression and engagement in embryonic morphogenesis. Epigenetic modifications, such as DNA methylation and histone acetylation, emerge as critical regulators, shaping the chromatin landscape to create a conducive environment for increased AI597479 transcription. Cellular signaling pathways, including cAMP and calcium signaling, play a vital role in the activation process, utilizing phosphorylation cascades to amplify AI597479 expression. Additionally, the modulation of gene regulation through interactions with DNA methyltransferases and retinoic acid receptors unveils a complex regulatory network that fine-tunes AI597479 activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Betaine | 107-43-7 | sc-214595 sc-214595A sc-214595B sc-214595C sc-214595D sc-214595E | 50 g 100 g 250 g 1 kg 2.5 kg 5 kg | $30.00 $40.00 $55.00 $160.00 $330.00 $580.00 | 2 | |
Betaine, a methyl donor, activates AI597479 by influencing DNA methylation patterns in the nucleus. This activation is facilitated by Betaine's role in providing methyl groups, leading to altered chromatin structure and enhanced AI597479 expression, promoting its involvement in embryonic morphogenesis. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Sodium Butyrate, a histone deacetylase inhibitor, activates AI597479 by enhancing histone acetylation. This activation results in a more permissive chromatin environment, facilitating increased transcription of AI597479 and promoting its role in embryonic morphogenesis. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A, a histone deacetylase inhibitor, activates AI597479 by promoting histone acetylation. This activation results in a more open chromatin structure, allowing increased accessibility for transcriptional machinery and enhancing AI597479 expression, thereby contributing to embryonic morphogenesis. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic Acid activates AI597479 through the retinoic acid receptor (RAR). RAR, upon binding to retinoic acid, forms a complex that activates transcription of AI597479, influencing embryonic morphogenesis. This activation is pivotal in regulating gene expression patterns during early development. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG, a component of green tea, activates AI597479 by inhibiting DNA methyltransferases, leading to altered DNA methylation patterns. This activation results in a permissive chromatin structure, enhancing AI597479 expression and promoting its involvement in embryonic morphogenesis. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine, a DNA methyltransferase inhibitor, activates AI597479 by inhibiting DNA methylation. This activation leads to a more permissive chromatin environment, facilitating increased AI597479 expression and contributing to embryonic morphogenesis. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Valproic Acid, a histone deacetylase inhibitor, activates AI597479 by promoting histone acetylation. This activation results in a more open chromatin structure, facilitating increased transcription of AI597479 and contributing to its role in embryonic morphogenesis. | ||||||
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $94.00 $259.00 | 2 | |
Ionomycin activates AI597479 by inducing calcium influx and subsequent activation of calcium/calmodulin-dependent protein kinase (CaMK). CaMK, in turn, phosphorylates transcription factors that enhance AI597479 expression, promoting its engagement in embryonic morphogenesis. | ||||||
Dimethyl Sulfoxide (DMSO) | 67-68-5 | sc-202581 sc-202581A sc-202581B | 100 ml 500 ml 4 L | $30.00 $115.00 $900.00 | 136 | |
DMSO activates AI597479 by modulating cellular signaling pathways. The activation involves DMSO-mediated alterations in intracellular signaling cascades, leading to enhanced AI597479 expression and its active participation in embryonic morphogenesis. | ||||||
1α,25-Dihydroxyvitamin D3 | 32222-06-3 | sc-202877B sc-202877A sc-202877C sc-202877D sc-202877 | 50 µg 1 mg 5 mg 10 mg 100 µg | $325.00 $632.00 $1428.00 $2450.00 $400.00 | 32 | |
Calcitriol activates AI597479 through the vitamin D receptor (VDR). Upon binding to VDR, the complex activates transcription of AI597479, influencing embryonic morphogenesis. This activation is crucial in regulating gene expression patterns during early development. | ||||||