C2orf49_AI597479 Inhibitors
AI597479, an expressed sequence predicted to play a role in embryonic morphogenesis, holds significance in the intricate orchestration of developmental processes. The predicted localization of AI597479 in the nucleus and its association with the tRNA-splicing ligase complex suggest its involvement in fundamental cellular activities, particularly transcription and translation regulation during embryonic development. The potential influence of AI597479 on embryonic morphogenesis implies a role in shaping the complex cellular events that drive the formation and differentiation of tissues and organs during early development. Inhibition strategies for AI597479 focus on targeting transcription and translation processes to modulate its expression and function. Compounds that directly impact RNA synthesis, such as those inhibiting RNA polymerase activity, can potentially disrupt the transcription of AI597479, limiting the availability of its mRNA and consequently affecting its contribution to embryonic morphogenesis.
Additionally, inhibitors that interfere with elongation or target specific RNA polymerases provide alternative avenues for controlling the expression of AI597479. Indirect inhibition through compounds affecting general cellular transcriptional dynamics, such as bacterial RNA polymerase inhibitors, introduces another layer of complexity to the potential regulatory mechanisms governing AI597479. These inhibitors may indirectly influence AI597479 by altering cellular transcriptional processes, thereby modulating its expression and potentially impacting its role in embryonic development.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D, an RNA synthesis inhibitor, directly targets transcription processes in the nucleus. By intercalating into DNA, Actinomycin D inhibits AI597479 expression at the transcriptional level. This inhibition disrupts the predicted role of AI597479 in embryonic morphogenesis by limiting the availability of its mRNA, potentially impacting early developmental processes. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Triptolide is an inhibitor of RNA polymerase II, influencing transcriptional activity. By targeting RNA polymerase II, Triptolide directly inhibits AI597479 expression at the transcriptional level. This inhibition perturbs the predicted involvement of AI597479 in embryonic morphogenesis by restricting the synthesis of its mRNA, potentially affecting key developmental processes during embryogenesis. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
α-Amanitin is a selective RNA polymerase II inhibitor, directly impacting transcription. By targeting RNA polymerase II, α-Amanitin inhibits AI597479 expression at the transcriptional level. This inhibition interferes with the predicted function of AI597479 in embryonic morphogenesis by limiting the synthesis of its mRNA, potentially influencing essential developmental pathways during embryogenesis. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
DRB is an inhibitor of transcription elongation through RNA polymerase II. By interfering with elongation, DRB directly inhibits AI597479 expression at the transcriptional level. This inhibition disrupts the predicted function of AI597479 in embryonic morphogenesis by limiting the availability of its mRNA, potentially impacting crucial developmental pathways during embryogenesis. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $254.00 | 41 | |
Flavopiridol is a cyclin-dependent kinase (CDK) inhibitor, influencing transcriptional regulation. By inhibiting CDKs, Flavopiridol directly impacts RNA polymerase II activity, leading to the inhibition of AI597479 expression at the transcriptional level. This disruption interferes with the predicted involvement of AI597479 in embryonic morphogenesis by limiting the synthesis of its mRNA, potentially influencing essential developmental pathways during embryogenesis. | ||||||
CX-5461 | 1138549-36-6 | sc-507275 | 5 mg | $240.00 | ||
CX-5461 is a selective RNA polymerase I inhibitor, impacting ribosomal RNA synthesis. By targeting RNA polymerase I, CX-5461 directly inhibits the expression of ribosomal RNA, potentially affecting AI597479 indirectly through alterations in the ribosomal machinery and translational regulation. This indirect inhibition may modulate the predicted function of AI597479 in embryonic morphogenesis by influencing global protein synthesis during key developmental processes. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
Camptothecin is a topoisomerase I inhibitor, influencing DNA topology and transcription. By inhibiting topoisomerase I, Camptothecin directly impacts RNA polymerase activity, leading to the inhibition of AI597479 expression at the transcriptional level. This interference disrupts the predicted involvement of AI597479 in embryonic morphogenesis by limiting the synthesis of its mRNA, potentially influencing essential developmental pathways during embryogenesis. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $99.00 | 5 | |
Cordycepin is an adenosine analog and RNA polymerase III inhibitor, impacting transcription. By inhibiting RNA polymerase III, Cordycepin directly inhibits AI597479 expression at the transcriptional level. This inhibition disrupts the predicted function of AI597479 in embryonic morphogenesis by limiting the availability of its mRNA, potentially impacting crucial developmental pathways during embryogenesis. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $95.00 $322.00 $663.00 $1438.00 | 6 | |
Rifampicin is an RNA polymerase inhibitor, specifically targeting bacterial RNA polymerase. By inhibiting RNA polymerase, Rifampicin indirectly influences AI597479 expression through potential alterations in general cellular transcription. This indirect inhibition may impact the predicted function of AI597479 in embryonic morphogenesis by modulating cellular transcriptional dynamics during key developmental processes. | ||||||