C20orf195 Activators
The activators of C20orf195 are a diverse set of chemical entities that engage with various biochemical pathways, influencing the protein's function or expression. Metformin, as a pharmacological activator of AMPK, can alter cellular energy homeostasis, thereby affecting gene expression profiles linked to metabolic pathways. This can lead to the activation or increased expression of C20orf195 if it plays a role in these pathways. Similarly, all-trans Retinoic Acid operates through nuclear hormone receptors to modulate gene expression, and if C20orf195 is responsive to such signals, its expression could be directly upregulated. On the other hand, natural compounds like Resveratrol and Spermidine target longevity and autophagy pathways, respectively, which could indirectly lead to modifications in the expression or function of C20orf195, depending on its role in these cellular processes.
Other molecules, such as Curcumin and Sodium Butyrate, interact with key signaling molecules and epigenetic regulators, underscoring the possibility of modulating gene expression through these pathways. Sodium Butyrate, specifically, can alter chromatin structure and accessibility, suggesting a mechanism for increasing C20orf195 expression if it is regulated epigenetically. Oltipraz and Dimethyl Fumarate, both activators of Nrf2, point towards oxidative stress response pathways as modulators of C20orf195, considering its involvement in cellular defense mechanisms. Troglitazone and Lithium Chloride implicate metabolic regulation and GSK-3 signaling in the modulation of C20orf195, with Lithium Chloride possibly enhancing the protein's stability or expression via inhibition of GSK-3. Capsaicin and Quercetin, affecting TRPV1 and kinase signaling pathways, respectively, highlight for altering C20orf195 activity through their varied influence on cell signaling networks. These activators do not represent direct binding interactors with C20orf195 but are indicative of the broader cellular milieu that can be modulated to influence the protein's activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Metformin | 657-24-9 | sc-507370 | 10 mg | $77.00 | 2 | |
Metformin activates AMP-activated protein kinase (AMPK), which can lead to the transcriptional regulation of genes involved in energy metabolism. If C20orf195 is implicated in these pathways, metformin can influence its activity or expression. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid modulates gene expression through retinoic acid receptors. If C20orf195 has retinoic acid response elements in its promoter region, its expression can be directly upregulated. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol activates sirtuins, influencing cellular longevity pathways. If C20orf195 is involved in these pathways, resveratrol can support its protein expression or activity through sirtuin-mediated mechanisms. | ||||||
Spermidine | 124-20-9 | sc-215900 sc-215900B sc-215900A | 1 g 25 g 5 g | $56.00 $595.00 $173.00 | ||
Spermidine is known to induce autophagy through inhibition of the acetyltransferase EP300. Enhanced autophagy can affect protein turnover, potentially upregulating C20orf195 if it is degraded by autophagic pathways. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin modulates various signaling pathways, including NF-κB. If C20orf195 is regulated by NF-κB signaling, curcumin can modulate its expression through these pathways. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Sodium butyrate is a histone deacetylase inhibitor, which can lead to the hyperacetylation of histones and activation of gene transcription. It may increase C20orf195 expression if histone acetylation is a regulatory mechanism for its gene. | ||||||
Oltipraz | 64224-21-1 | sc-205777 sc-205777A | 500 mg 1 g | $286.00 $622.00 | ||
Oltipraz activates Nrf2 signaling, a pathway involved in the cellular response to oxidative stress. If C20orf195 plays a role in this response, oltipraz can support its expression or activity. | ||||||
Troglitazone | 97322-87-7 | sc-200904 sc-200904B sc-200904A | 5 mg 10 mg 25 mg | $108.00 $200.00 $426.00 | 9 | |
A PPARγ agonist, troglitazone can modulate lipid metabolism pathways, which could affect C20orf195 if it is associated with lipid metabolic processes. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium chloride can inhibit GSK-3, leading to the stabilization of β-catenin and modulation of Wnt signaling. If C20orf195 is downstream of Wnt signaling, this could enhance its stability or expression. | ||||||
Dimethyl fumarate | 624-49-7 | sc-239774 | 25 g | $27.00 | 6 | |
Dimethyl fumarate activates the Nrf2 pathway, which could lead to increased expression of antioxidant response genes. C20orf195 could be upregulated if it is part of this response. | ||||||