C20orf195 Inhibitors
C20orf195 inhibitors are a range of chemicals targeting cellular pathways, the interaction with which could modulate C20orf195's activity. Chemicals such as LY294002 and Wortmannin can halt the PI3K-Akt pathway, which is integral for cell survival, growth, and proliferation. If C20orf195 were part of this pathway, its functional expression would be suppressed. Similarly, U0126 and PD98059 target the MAPK pathway by inhibiting MEK and ERK, respectively. If C20orf195 is regulated or activated by these kinases, its functionality would be compromised.
Phosphorylation-related inhibitors like Staurosporine and SP600125 block multiple kinases and JNK, respectively. Should C20orf195 require such post-translational modifications for its function or activation, these inhibitors would halt such processes. Additionally, inhibitors like Y-27632 and Blebbistatin that focus on cellular dynamics by blocking ROCK and myosin II can affect C20orf195 if it is involved in processes like cell motility or shape maintenance. Lastly, phosphatase inhibitors like Calyculin A and Okadaic Acid have the ability to interfere with the phosphorylation state of C20orf195, affecting its activity accordingly.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Inhibits PI3K, blocking downstream Akt signaling, possibly leading to downregulation of C20orf195 if part of this route. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Targets multiple kinases, disrupting kinase-mediated phosphorylation that C20orf195 may be dependent on. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Blocks JNK activity, thereby preventing the JNK-dependent phosphorylation events that might involve C20orf195. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Inhibits ROCK, affecting the cytoskeleton and potentially the localization or function of C20orf195 if it is involved in cellular dynamics. | ||||||
IWP-2 | 686770-61-6 | sc-252928 sc-252928A | 5 mg 25 mg | $94.00 $286.00 | 27 | |
Inhibits Wnt secretion, thereby negating the potential role of C20orf195 in the Wnt signaling pathway. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Blocks ERK, affecting MAPK pathways and consequently the function or regulation of C20orf195 if part of this pathway. | ||||||
(±)-Blebbistatin | 674289-55-5 | sc-203532B sc-203532 sc-203532A sc-203532C sc-203532D | 5 mg 10 mg 25 mg 50 mg 100 mg | $179.00 $307.00 $455.00 $924.00 $1689.00 | 7 | |
Inhibits myosin II, affecting cellular motility, which can impact C20orf195 if involved in these processes. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Inhibits mTOR, thereby affecting protein synthesis pathways and potentially inhibiting C20orf195 if it is synthesized in response to mTOR activation. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Another PI3K inhibitor, with similar effects on C20orf195 as LY294002 if involved in the Akt pathway. | ||||||
Calyculin A | 101932-71-2 | sc-24000 sc-24000A sc-24000B sc-24000C | 10 µg 100 µg 500 µg 1 mg | $160.00 $750.00 $1400.00 $3000.00 | 59 | |
Inhibits PP1/PP2A phosphatases, affecting the phosphorylation state of proteins, including potentially C20orf195. | ||||||