C20orf112 Inhibitors
C20orf112, officially named "Chromosome 20 Open Reading Frame 112," is a protein encoded by the C20orf112 gene located, as the name suggests, on chromosome 20. It is one of many proteins within the human genome that is denoted by an "open reading frame" (ORF) classification, suggesting that the region of DNA is known to be transcribed into RNA and has the potential to be translated into a protein, but its function has not been well-characterized.When proteins are defined this way, they may be studied for common structural motifs or domains that can provide clues to their function. Bioinformatic tools can compare the amino acid sequence of C20orf112 to known proteins to find similarities that might suggest a role in cellular processes such as signaling, structural integrity, enzymatic activity, or the regulation of gene expression.
Given its localization and the functions typically associated with nucleolar proteins, NOL4L may participate in critical cellular processes such as cell cycle control, stress responses, and cellular growth. Nucleolar proteins also have been implicated in the assembly of signal recognition particles, which play a key role in targeting proteins to the endoplasmic reticulum.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Actinomycin D binds to DNA and inhibits RNA polymerase, affecting RNA synthesis. This could indirectly affect NOL4L by altering the nucleolar processes associated with RNA processing. | ||||||
CX-5461 | 1138549-36-6 | sc-507275 | 5 mg | $245.00 | ||
CX-5461 inhibits RNA Polymerase I, specifically targeting rRNA synthesis in the nucleolus. This might indirectly impact NOL4L functions related to nucleolar organization and RNA processing. | ||||||
BMH-21 | 896705-16-1 | sc-507460 | 10 mg | $165.00 | ||
BMH-21 is an RNA Polymerase I inhibitor, which leads to the disruption of nucleolar structure and function. Its effects could indirectly influence NOL4L-related nucleolar activities. | ||||||
Mycophenolic acid | 24280-93-1 | sc-200110 sc-200110A | 100 mg 500 mg | $69.00 $266.00 | 8 | |
Mycophenolic Acid inhibits inosine monophosphate dehydrogenase, impacting RNA and DNA synthesis. This might indirectly affect NOL4L by altering nucleolar functions. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $37.00 $152.00 | 11 | |
5-Fluorouracil is a nucleotide analog that inhibits thymidylate synthase, impacting DNA and RNA synthesis. This might indirectly affect NOL4L by disrupting nucleolar activities. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $176.00 $426.00 | 43 | |
Doxorubicin intercalates into DNA and inhibits topoisomerase II, affecting DNA and RNA synthesis. This could indirectly impact NOL4L's function in the nucleolus. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $58.00 $186.00 $94.00 | 21 | |
Camptothecin inhibits topoisomerase I, affecting DNA replication and transcription. This might indirectly influence NOL4L through changes in nucleolar dynamics. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $43.00 $189.00 $316.00 $663.00 | 6 | |
DRB inhibits RNA polymerase II, affecting mRNA synthesis. This could have indirect effects on NOL4L's role in nucleolar processes related to RNA metabolism. | ||||||
Ribavirin | 36791-04-5 | sc-203238 sc-203238A sc-203238B | 10 mg 100 mg 5 g | $63.00 $110.00 $214.00 | 1 | |
Ribavirin is a nucleoside analog that inhibits RNA synthesis. Its impact on nucleolar RNA processing could indirectly influence NOL4L functions. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $69.00 | 2 | |
Chloroquine can accumulate in lysosomes and inhibit lysosomal enzymes, indirectly affecting cellular processes including those in the nucleolus, potentially impacting NOL4L. | ||||||