C20orf112 Inhibitors

C20orf112, officially named "Chromosome 20 Open Reading Frame 112," is a protein encoded by the C20orf112 gene located, as the name suggests, on chromosome 20. It is one of many proteins within the human genome that is denoted by an "open reading frame" (ORF) classification, suggesting that the region of DNA is known to be transcribed into RNA and has the potential to be translated into a protein, but its function has not been well-characterized.When proteins are defined this way, they may be studied for common structural motifs or domains that can provide clues to their function. Bioinformatic tools can compare the amino acid sequence of C20orf112 to known proteins to find similarities that might suggest a role in cellular processes such as signaling, structural integrity, enzymatic activity, or the regulation of gene expression.

Given its localization and the functions typically associated with nucleolar proteins, NOL4L may participate in critical cellular processes such as cell cycle control, stress responses, and cellular growth. Nucleolar proteins also have been implicated in the assembly of signal recognition particles, which play a key role in targeting proteins to the endoplasmic reticulum.