C1orf151-NBL1 Activators
The functional activity of the C1orf151-NBL1 fusion protein can be influenced by various chemical compounds that target the distinct functionalities of the C1orf151 and NBL1 gene products. Retinoic acid and Genistein, known for their roles in gene expression and cell differentiation, might enhance the NBL1 component's involvement in developmental processes. Retinoic acid's influence on gene expression and Genistein's tyrosine kinase inhibitory action could modulate pathways relevant to cell differentiation and development, aligning with NBL1's biological role. Forskolin, through its effect on increasing cAMP levels, and Dibutyryl-cAMP, a cAMP analog, could potentially modulate the C1orf151 component's function in cellular signaling processes influenced by cAMP. Curcumin, with its wide-ranging effects on cell signaling, including pathways involved in proliferation and apoptosis, could impact both C1orf151 and NBL1 components, influencing various cellular processes.
Compounds like LY294002, a PI3K inhibitor, and Rapamycin, an mTOR inhibitor, could play a role in modulating cell survival and proliferation pathways, potentially affecting the functionality of both components of the fusion protein. Trichostatin A, an HDAC inhibitor, may influence gene expression and protein acetylation, thus affecting both C1orf151 and NBL1 functions within the fusion protein. Additionally, Spermidine and Resveratrol, known for promoting autophagy and influencing cellular aging and differentiation, might support the NBL1 component's involvement in development within the fusion protein. Epigallocatechin gallate (EGCG), by modulating cell proliferation and apoptosis pathways, and 17-AAG (Tanespimycin), an HSP90 inhibitor affecting protein folding, could also influence the functional activity of both components of the fusion protein. Together, these compounds illustrate the complexity in modulating the activity of the C1orf151-NBL1 fusion protein, reflecting the diverse functional aspects and regulatory mechanisms of its constituent parts.
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid influences gene expression and is involved in cell differentiation. It may enhance the NBL1 component of the C1orf151-NBL1 fusion protein, potentially affecting developmental processes where NBL1 is implicated. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin modulates various signaling pathways, including those involved in cell proliferation and apoptosis. This could affect both C1orf151 and NBL1 components of the fusion protein, influencing cellular processes. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein, a tyrosine kinase inhibitor, can modulate cell signaling pathways. This might affect the NBL1 component of the C1orf151-NBL1 fusion, particularly in pathways related to cell differentiation and development. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002, a PI3K inhibitor, could influence cellular signaling pathways related to cell survival and proliferation, potentially affecting both C1orf151 and NBL1 components of the fusion protein. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits mTOR, involved in cell growth and proliferation. This inhibition could influence the functions of both C1orf151 and NBL1 components in the fusion protein, particularly in pathways related to cell growth. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A is an HDAC inhibitor, affecting gene expression and protein acetylation. This could influence the function of both C1orf151 and NBL1 in the fusion protein. | ||||||
Spermidine | 124-20-9 | sc-215900 sc-215900B sc-215900A | 1 g 25 g 5 g | $56.00 $595.00 $173.00 | ||
Spermidine promotes autophagy and may influence cellular aging and differentiation processes, potentially supporting the NBL1 component's role in development within the fusion protein. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol activates SIRT1, influencing gene expression and cellular aging processes. This could support the NBL1 component's role in developmental processes in the C1orf151-NBL1 fusion protein. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Epigallocatechin gallate (EGCG) modulates several signaling pathways, including those related to cell proliferation and apoptosis. EGCG could influence both components of the fusion protein in cellular signaling processes. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $45.00 $130.00 $480.00 $4450.00 | 74 | |
Dibutyryl-cAMP, a cAMP analog, might enhance the function of the C1orf151 component in cAMP-dependent cellular processes that might be influenced by the fusion protein. | ||||||