C14orf138 Activators
C14orf138, a protein lysine methyltransferase, sees its enzymatic activity modulated by a range of molecular enhancers that impact key biochemical pathways. Methyl donors ubiquitous within cellular processes are central to the methylation reactions facilitated by C14orf138, effectively boosting its functional capacity. Furthermore, the enzyme's structural integrity and catalytic activity may be bolstered by certain metal ions which serve as cofactors, strengthening the enzyme's architecture or directly engaging in the methylation process. These ions, along with donors from metabolic cycles that supply additional methyl groups, ensure that C14orf138 has the resources needed for an increased rate of methylation.
Cellular messengers that elevate after certain stimuli can activate kinase pathways, leading to the potential phosphorylation and subsequent activation of proteins like C14orf138. Meanwhile, changes in the methylation landscape, due to alterations in gene expression patterns, may indirectly elevate the expression levels of C14orf138. Modulation of chromatin structure to favor gene expression could also result in higher levels of this enzyme. Furthermore, by-products of the methylation process itself might act as regulators, maintaining the balance of enzymatic activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ademetionine | 29908-03-0 | sc-278677 sc-278677A | 100 mg 1 g | $184.00 $668.00 | 2 | |
Serves as a methyl donor in various methylation reactions, including the methylation of proteins. C14orf138's activity is increased through methylation. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $116.00 $179.00 $265.00 $369.00 $629.00 $1150.00 | ||
Is a second messenger that can activate protein kinases, potentially enhancing the methylation activity of C14orf138 through phosphorylation. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $57.00 $191.00 $302.00 $450.00 $1800.00 $3570.00 $10710.00 | 4 | |
NAD+ is a coenzyme in redox reactions. It may indirectly upregulate C14orf138 activity by altering the cellular redox state, which affects methylation processes. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc acts as a cofactor for various enzymes, it may enhance the catalytic activity of C14orf138 by stabilizing its structure or interacting with substrates. | ||||||
Magnesium chloride | 7786-30-3 | sc-255260C sc-255260B sc-255260 sc-255260A | 10 g 25 g 100 g 500 g | $28.00 $35.00 $48.00 $125.00 | 2 | |
Magnesium is a cofactor that is essential for the activity of many enzymes, possibly including C14orf138, by supporting its enzymatic function. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Inhibits DNA methyltransferases, potentially leading to upregulation of protein expression including C14orf138 through epigenetic changes. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
May upregulate C14orf138 by altering chromatin structure and enhancing gene expression. | ||||||
Homocysteine | 6027-13-0 | sc-507315 | 250 mg | $195.00 | ||
As a product inhibitor of methyltransferases, it can provide feedback that may enhance the activity of other methyltransferases like C14orf138. | ||||||
Betaine | 107-43-7 | sc-214595 sc-214595A sc-214595B sc-214595C sc-214595D sc-214595E | 50 g 100 g 250 g 1 kg 2.5 kg 5 kg | $31.00 $41.00 $56.00 $163.00 $337.00 $592.00 | 2 | |
Acts as a methyl donor in the methionine cycle, potentially providing more methyl groups for C14orf138 to use in methylation reactions. | ||||||
Dimethyl Sulfoxide (DMSO) | 67-68-5 | sc-202581 sc-202581A sc-202581B | 100 ml 500 ml 4 L | $31.00 $117.00 $918.00 | 136 | |
As a solvent, it can affect the conformation of proteins and could indirectly increase the activity of C14orf138 by stabilizing its active form. | ||||||