BNIPL-2 Activators
The term BNIPL-2 Activators refers to a specific category of chemical compounds designed to modulate the activity of the BNIPL-2 protein. BNIPL-2, also known as BCL2/adenovirus E1B 19 kDa protein-interacting protein 2-like, is a protein that interacts with members of the BCL2 family, which are key regulators of apoptosis (programmed cell death). The precise biological function of BNIPL-2 is not fully elucidated, and ongoing research aims to uncover its roles in cellular processes. Activators within the BNIPL-2 Activators class typically consist of small molecules or chemical agents engineered to interact with the BNIPL-2 protein, with the objective of enhancing its functional capabilities or influencing its interactions with other cellular components. These activators are valuable tools for researchers to manipulate BNIPL-2-related processes and explore its potential functions.
The mechanism of action for BNIPL-2 Activators can involve several levels of protein regulation. These compounds may influence the conformation of the BNIPL-2 protein, potentially enhancing its ability to interact with other cellular proteins, including those involved in apoptosis regulation. Alternatively, they could affect post-translational modifications of BNIPL-2, such as phosphorylation or ubiquitination, which can modulate its stability or subcellular localization. Researchers and scientists employ BNIPL-2 Activators in molecular and cell biology studies to investigate the role of BNIPL-2 in apoptosis regulation, cellular stress responses, and potential implications in cellular homeostasis. By selectively modulating the protein's activity, researchers can gain insights into its functions, regulatory mechanisms, and potential involvement in apoptosis pathways, contributing to a deeper understanding of the molecular processes involving BNIPL-2 and its impact on cell fate decisions. Overall, BNIPL-2 Activators provide valuable tools for unraveling the complexities of BNIPL-2 biology and its interactions with other cellular components.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Staurosporine is a potent protein kinase inhibitor that induces apoptosis in a wide range of cell types, potentially affecting the expression of apoptosis-related genes like BNIPL-2. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $51.00 $231.00 $523.00 | 63 | |
Etoposide, a topoisomerase II inhibitor, induces DNA damage leading to apoptosis, which could hypothetically upregulate BNIPL-2 as part of the cellular DNA damage response. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $176.00 $426.00 | 43 | |
Doxorubicin generates free radicals and intercalates into DNA, causing apoptosis and potentially influencing BNIPL-2 expression in response to genotoxic stress. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
Thapsigargin induces ER stress by blocking calcium pumps in the ER, leading to apoptosis, which might hypothetically increase BNIPL-2 expression as part of the unfolded protein response. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
Tunicamycin inhibits N-linked glycosylation, inducing ER stress and potentially upregulating apoptosis-related genes like BNIPL-2 as part of the ER-associated degradation pathway. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane, a compound in cruciferous vegetables, activates NRF2 and can induce apoptosis in cancer cells, potentially affecting BNIPL-2 expression as part of its anti-cancer mechanisms. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin effects potentially modulating the expression of genes involved in cell survival pathways, including hypothetically BNIPL-2. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol, a polyphenol from red wine, exhibits anti-cancer properties by inducing apoptosis, which might influence BNIPL-2 expression as part of its effects on cell survival. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $138.00 $380.00 | 101 | |
Cisplatin, a chemotherapy drug, induces DNA damage and apoptosis, potentially leading to changes in the expression of apoptosis-related genes like BNIPL-2. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $58.00 $186.00 $94.00 | 21 | |
Camptothecin, a topoisomerase I inhibitor, induces DNA damage and apoptosis, which could hypothetically affect BNIPL-2 expression as part of the cellular response to DNA damage. | ||||||