Caspase recruitment domain family member 19 (CARD19) is a protein that belongs to the CARD-containing protein family. Proteins in this family are characterized by the presence of a caspase recruitment domain, which is a specialized type of protein interaction motif. This domain is typically involved in the formation of multiprotein complexes that can initiate or regulate inflammation and apoptosis.
CARD19, like other CARD-containing proteins, is thought to participate in the signaling pathways that control these vital cellular processes. Specifically, CARD domains often mediate the assembly of signaling complexes that lead to the activation of NF-κB, a transcription factor that plays a key role in immune and inflammatory responses, as well as caspases, which are enzymes central to the execution phase of cell apoptosis.The precise biological functions of CARD19 are not as well-characterized as some other members of the CARD family. However, it is likely involved in immune system regulation, potentially acting as an adaptor molecule that assembles protein complexes in response to internal or external stress signals, thereby influencing the activation of caspases and the subsequent induction of inflammatory or cell death pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $176.00 $426.00 | 43 | |
Doxorubicin induces DNA damage, which can upregulate apoptotic signaling pathways. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $51.00 $231.00 $523.00 | 63 | |
Etoposide causes DNA damage by inhibiting topoisomerase II, potentially increasing CARD19 expression. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $58.00 $186.00 $94.00 | 21 | |
Camptothecin inhibits topoisomerase I, leading to DNA damage and possible upregulation of apoptosis-related proteins. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $31.00 $61.00 $95.00 | 28 | |
As an inducer of oxidative stress, it may enhance the expression of genes involved in the cellular stress response. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $138.00 $380.00 | 101 | |
Cisplatin forms DNA adducts, triggering apoptosis and possibly affecting CARD19 expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin can modulate various signaling pathways, potentially influencing apoptotic protein expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol affects several signaling pathways and may have a role in inducing apoptosis-related genes. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane activates stress response pathways, which could include the upregulation of CARD19. | ||||||
Arsenic(III) oxide | 1327-53-3 | sc-210837 sc-210837A | 250 g 1 kg | $89.00 $228.00 | ||
It induces apoptosis in certain cells, which may involve the upregulation of CARD family members. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $94.00 $213.00 | 33 | |
Methotrexate can lead to cellular stress and apoptosis, potentially affecting CARD19 expression. | ||||||