Date published: 2026-5-18

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BinCARD Activators

Caspase recruitment domain family member 19 (CARD19) is a protein that belongs to the CARD-containing protein family. Proteins in this family are characterized by the presence of a caspase recruitment domain, which is a specialized type of protein interaction motif. This domain is typically involved in the formation of multiprotein complexes that can initiate or regulate inflammation and apoptosis.

CARD19, like other CARD-containing proteins, is thought to participate in the signaling pathways that control these vital cellular processes. Specifically, CARD domains often mediate the assembly of signaling complexes that lead to the activation of NF-κB, a transcription factor that plays a key role in immune and inflammatory responses, as well as caspases, which are enzymes central to the execution phase of cell apoptosis.The precise biological functions of CARD19 are not as well-characterized as some other members of the CARD family. However, it is likely involved in immune system regulation, potentially acting as an adaptor molecule that assembles protein complexes in response to internal or external stress signals, thereby influencing the activation of caspases and the subsequent induction of inflammatory or cell death pathways.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Doxorubicin

23214-92-8sc-280681
sc-280681A
1 mg
5 mg
$176.00
$426.00
43
(3)

Doxorubicin induces DNA damage, which can upregulate apoptotic signaling pathways.

Etoposide (VP-16)

33419-42-0sc-3512B
sc-3512
sc-3512A
10 mg
100 mg
500 mg
$51.00
$231.00
$523.00
63
(1)

Etoposide causes DNA damage by inhibiting topoisomerase II, potentially increasing CARD19 expression.

Camptothecin

7689-03-4sc-200871
sc-200871A
sc-200871B
50 mg
250 mg
100 mg
$58.00
$186.00
$94.00
21
(2)

Camptothecin inhibits topoisomerase I, leading to DNA damage and possible upregulation of apoptosis-related proteins.

Hydrogen Peroxide

7722-84-1sc-203336
sc-203336A
sc-203336B
100 ml
500 ml
3.8 L
$31.00
$61.00
$95.00
28
(1)

As an inducer of oxidative stress, it may enhance the expression of genes involved in the cellular stress response.

Cisplatin

15663-27-1sc-200896
sc-200896A
100 mg
500 mg
$138.00
$380.00
101
(4)

Cisplatin forms DNA adducts, triggering apoptosis and possibly affecting CARD19 expression.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin can modulate various signaling pathways, potentially influencing apoptotic protein expression.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol affects several signaling pathways and may have a role in inducing apoptosis-related genes.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$153.00
$292.00
$489.00
$1325.00
$8465.00
$933.00
22
(1)

Sulforaphane activates stress response pathways, which could include the upregulation of CARD19.

Arsenic(III) oxide

1327-53-3sc-210837
sc-210837A
250 g
1 kg
$89.00
$228.00
(0)

It induces apoptosis in certain cells, which may involve the upregulation of CARD family members.

Methotrexate

59-05-2sc-3507
sc-3507A
100 mg
500 mg
$94.00
$213.00
33
(5)

Methotrexate can lead to cellular stress and apoptosis, potentially affecting CARD19 expression.